Ii. the Relation between Capillary Pressure and the Rate at Which Fluid Passes through the Walls of Single Capillaries
Ii. the Relation between Capillary Pressure and the Rate at Which Fluid Passes through the Walls of Single Capillaries
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发表时间：
2003
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通讯作者：
E. Landis
中科院分区：
文献类型：
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作者：
E. Landis
先前用微量注射方法(Landis，1926a)对青蛙肠系膜血管的研究表明，平均毛细血管压和血浆蛋白的渗透压之间是平衡的。细动脉毛细血管的平均压力高于静脉毛细血管的平均压力--血浆胶体的渗透压被认为是支持Starling(1896)假说的证据。根据这一观点，当毛细血管压力高于血浆蛋白质的渗透压时，液体离开血液；当毛细血管压力降至该水平以下时，液体进入血液。本文介绍了在控制毛细压力的情况下，定量研究毛细管壁渗透性的进一步实验。实验分为两组。在第一种方法中，通过注入某些易见染料的溶液来间接识别流体通过毛细管壁的运动；在第二种方法中，通过毛细血管内小体的各自稀释或浓度直接测量流体通过内皮细胞的流入或流出的速度。这两种方法都进一步证明了一种更直接的特征，即流体的运动取决于毛细血管压力相对于血浆胶体的有效渗透压的水平。一、毛细管压力与扩张的关系染料溶液通过217的移动速度
Previous work on the vessels of the frog mesentery by the micro-injection method (Landis, 1926a) has indicated a balance between the average capillary blood pressure and the osmotie pressure of the plasma proteins. The fact that the average pressure in the arteriolar capillary is aboveand in the venous capillary is below-the osmotic pressure of the plasma colloids is regarded as evidence favoring the hypothesis of Starling (1896). According to this view fluid leaves the blood stream when capillary pressure rises above the osmotic pressure of the plasma proteins, to which the normal endothelium is impermeable; and enters the blood stream when the capillary pressure falls below that level. This paper deals with further experiments designed to study the permeability of the capillary wall in a quantitative manner, with control of capillary pressure. The experiments fall into two groups. In the first the movement of fluid through the capillary wall is identified indirectly by injecting solutions of certain easily visible dyes; in the second the rate of fluid passage inward or outward through the endothelium is measured directly by the respective dilution or concentration of the corpuscles in the capillary. Both methods provide further evidence of a more direct character favoring the view that fluid movement depends upon the level of capillary pressure in relation to the effective osmotic pressure of the plasma colloids. I. THEPASSAGEOF DYESOLUTIONSINRELATIONTOCAPILLARY PRESSURE AND DILATATION. The rate of movement of dye solutions through the 217