An Imperative Need for Further Genetic Studies of Alopecia Areata.
An Imperative Need for Further Genetic Studies of Alopecia Areata.
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DOI：
10.1016/j.jisp.2020.04.003
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发表时间：
2020-11
期刊：
影响因子：
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通讯作者：
Petukhova L
中科院分区：
文献类型：
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作者：
Petukhova L
Human genetic studies of diseases that are multifactorial and prevalent have generated a wealth of knowledge about the genetic architecture of chronic diseases. Generalizable attributes are shaping the development of models to explain how the human genome influences our health and can be leveraged to improve it. Importantly, both rare and common genetic variants contribute to disease risk and provide complementary information. While initial genetic studies of alopecia areata have yielded insight with high clinical impact, there remains a number of important unanswered questions pertaining to disease biology and patient care that could be addressed by further genetic investigations.
