EFFECT OF DORSOLATERAL HYPOTHALAMIC LESIONS ON SODIUM APPETITE ELICITED BY DESOXYCORTICOSTERONE AND BY ACUTE HYPONATREMIA.
EFFECT OF DORSOLATERAL HYPOTHALAMIC LESIONS ON SODIUM APPETITE ELICITED BY DESOXYCORTICOSTERONE AND BY ACUTE HYPONATREMIA.
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下丘脑背外侧损伤对去氧皮质酮和急性低钠血症引起的钠食欲的影响。
DOI：
10.1037/h0048232
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发表时间：
1964
期刊：
影响因子：
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通讯作者：
G. Wolf
中科院分区：
文献类型：
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作者：
G. Wolf
在大鼠下丘脑外侧背侧部位损伤，并让其有时间从损伤引起的暂时性失食和失语中恢复过来。采用标准的2瓶试验条件，观察去氧皮质酮注射前后的生理盐水偏好。病变对正常的弱盐水偏好或浓盐水厌恶没有影响，但严重破坏了去氧皮质酮治疗增强盐水摄入量的作用。与正常大鼠相比，腹膜透析引起的低钠血症对损伤大鼠的生理盐水摄入量没有影响。（PsycINFO数据库记录(c) 2016 APA，版权所有）
Rats were lesioned in the dorsal part of the lateral area of the hypothalamus and allowed time to recover from the temporary adipsia and aphagia produced by the lesions. Saline preference was observed before and after injection of desoxycorticosterone using standard 2-bottle testing conditons. The lesions had no effect upon the normal preference for weak saline or aversion to strong saline but severely disrupted the potentiation of saline intake by desoxycorticosterone treatment. In contrast with normal rats, hyponatremia induced by intraperitoneal dialysis against glucose, had no effect upon the saline intake of the lesioned rats.(PsycINFO Database Record (c) 2016 APA, all rights reserved)