Fatigue in Psychiatric HIV Patients: A Pilot Study of Psychological Correlates

Fatigue in Psychiatric HIV Patients: A Pilot Study of Psychological Correlates
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DOI:
10.1176/appi.psy.50.5.455
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发表时间:
2009-09-01
期刊:
影响因子:
3.4
通讯作者:
Freudenreich, Oliver
Freudenreich, Oliver
中科院分区:
医学4区
文献类型:
--
作者:
Paddison, Johanna;Fricchione, Gregory;Freudenreich, Oliver

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背景资料:尽管艾滋病毒感染的病毒管理现在更有效,但临床观察表明,疲劳仍然是相当一部分患者的问题。目的:作者描述了有精神病合并症的HIV患者疲劳的患病率和严重程度,并检查了疲劳的心理相关性。方法:作者采用身份-后果疲劳量表对38名连续接受精神病治疗的HIV患者的疲劳进行了全面评估。结果如下:大约80%的患者报告至少有中度疲劳感,大约25%的患者认为疲劳严重影响了他们的日常功能。抑郁、焦虑和感知压力解释了20%至75%的疲劳评分差异。讨论内容:结果表明,在有效的抗逆转录病毒治疗的时代,疲劳是普遍的,相关的,并与心理疾病有关。识别和治疗这些合并症可能对减少这种疲劳很重要。(Psychosomatics 2009; 50:455-460)
Background: Even though viral management of HIV infection is now more effective, clinical observations suggest that fatigue remains a problem for a substantial proportion of patients. Objective: The authors delineated prevalence and severity of fatigue in HIV patients with psychiatric comorbidities and examined psychological correlates of fatigue. Method: The authors comprehensively assessed fatigue in 38 consecutive HIV patients referred for psychiatric treatment with the Identity-Consequence Fatigue Scale. Results: About 80% of patients reported at least moderate feelings of fatigue, and about 25% judged that fatigue was severely affecting their daily functioning. Depression, anxiety, and perceived stress explained between 20% and 75% of the variance in fatigue ratings. Discussion: The results suggest that fatigue in the era of effective antiretroviral treatment is prevalent, relevant, and related to psychological morbidities. Recognition and treatment of these comorbidities may be important in reducing this fatigue. (Psychosomatics 2009; 50: 455-460)