Can Automated Text Messaging Successfully Monitor Antibiotic Adherence for Urban Adolescents and Young Women Managed for Pelvic Inflammatory Disease in the Outpatient Setting.
Can Automated Text Messaging Successfully Monitor Antibiotic Adherence for Urban Adolescents and Young Women Managed for Pelvic Inflammatory Disease in the Outpatient Setting.
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DOI：
10.17140/pnnoj-8-135
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Trent, Maria
中科院分区：
文献类型：
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作者：
Rice, Bria;Perin, Jamie;Huettner, Steven;Butz, Arlene;Yusuf, Hasiya E;Trent, Maria
本研究评估了患者对盆腔炎（PID）自我护理支持的自动短信系统的反应，并测量了文本报告依从性的可靠性。年龄在13-25岁的轻度至中度PID患者从城市，学术门诊设置招募。入选患者接受抗生素治疗，并随机分为标准治疗组或干预组。在14天的治疗期间，干预组的参与者接受了基于社区的护理访问和每日短信药物提醒，并在晚上提示报告服用的剂量。在随机分配到干预组的97名参与者中，91名（94%）有资格进行分析。大多数是非洲裔美国人和低收入，平均年龄为18.3（SD=2.2）岁。参与者对所有剂量询问信息的约53%（SD=34%）做出了回应。在治疗期间，反应性以每天约2.2%的速度衰减。93%（n=85）的分析干预组返回接受2周随访。尽管总体依从性和一般反应性，文本报告和自我报告的药物依从性没有很好的相关性（r=0.37，p<0.001）。我们的研究结果表明，短信是一个可行的策略，以达到城市青少年正在管理的复杂性传播感染门诊设置。然而，患者对自我护理文本消息的响应确实不同，限制了该技术的依从性监测能力。鉴于未回复短信的数量和不完整的文本报告依从性数据，临床试验中需要额外的措施来评估青少年对PID药物的依从性。
This study evaluates patient responsiveness to an automated text messaging system for pelvic inflammatory disease (PID) self-care support, and measures the reliability of text-reported adherence. Patients aged 13–25-years with mild to moderate PID were recruited from urban, academic outpatient settings. Enrolled patients received antibiotics and were randomized into a standard of care or intervention group. During a 14-day treatment period, participants in the intervention arm received a community-based nursing visit and daily text message medication reminders with evening prompts to report the number of doses taken. Of the 97 participants randomized into the intervention arm, 91 (94%) were eligible for analysis. Most were African American and low income, with a mean age of 18.3 (SD=2.2) years. Participants responded to ~53% (SD=34%) of all dosage inquiry messages. Responsiveness attenuated at approximately 2.2% per day over the treatment period. Ninety-three percent (n=85) of the analyzed intervention arm returned for the two-week follow-up. Despite overall adherence and general responsiveness, text-reported and self-reported medication adherence were not well correlated (r=0.37, p<0.001). Our findings show that text messaging is a feasible strategy for reaching urban adolescents being managed for complicated sexually transmitted infections in outpatient settings. However, patient responsiveness to self-care text messages do vary, limiting the adherence monitoring capacity of this technology. Given the number of unanswered text messages and incomplete text-reported adherence data, additional measures to assess adolescents’ adherence to PID medications are needed in clinical trials.