INTESTINAL-ABSORPTION AND BIOMAGNIFICATION OF ORGANOCHLORINES
INTESTINAL-ABSORPTION AND BIOMAGNIFICATION OF ORGANOCHLORINES
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DOI：
10.1002/etc.5620120316
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发表时间：
1993-03-01
影响因子：
4.1
通讯作者：
HAFFNER, GD
中科院分区：
文献类型：
--
作者：
GOBAS, FAPC;MCCORQUODALE, JR;HAFFNER, GD
为探讨有机氯化合物的肠道吸收和生物放大机制，测定了金鱼（Carassius auratus）对不同脂肪含量饲料中几种有机氯化合物的吸收速率。结果表明，肠道吸收主要是由化学扩散，而不是脂质共转运控制。婴儿的化学品摄取数据表明，生物放大作用是由食物在胃肠道消化引起的。研究结果进行了讨论的背景下，两个相互矛盾的理论的生物放大作用的机制，并提出了一个机械模型的饮食摄取和生物放大作用的有机化学品在鱼类和哺乳动物。
Dietary uptake rates of several organochlorines from diets with different lipid contents were measured in goldfish (Carassius auratus) to investigate the mechanism of intestinal absorption and biomagnification of organic chemicals. The results suggest that intestinal absorption is predominantly controlled by chemical diffusion rather than lipid cotransport. Data for chemical uptake in human infants are presented to illustrate that biomagnification is caused by the digestion of food in the gastrointestinal tract. The findings are discussed in the context of two conflicting theories for the mechanism of biomagnification, and a mechanistic model is presented for the dietary uptake and biomagnification of organic chemicals in fish and mammals.