Structural and Functional Aspects of the Interaction of Inflammatory Cells with the Blood‐Brain Barrier in Experimental Brain Inflammation

Structural and Functional Aspects of the Interaction of Inflammatory Cells with the Blood‐Brain Barrier in Experimental Brain Inflammation
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实验性脑炎症中炎症细胞与血脑屏障相互作用的结构和功能

DOI:
10.1111/j.1750-3639.1991.tb00645.x
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发表时间:
1991
期刊:
影响因子:
6.4
通讯作者:
A. Lossinsky
A. Lossinsky
中科院分区:
医学2区
文献类型:
--
作者:
H. Wiśniewski;A. Lossinsky

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Interaction between various subclasses of inflammatory cells (ICs) and endothelial cells (ECs) lining selective blood vessels of the mammalian blood‐brain barrier (BBB) is an initial, important event during inflammatory conditions of the central nervous system (CNS). In this review, we will present a brief ultracytochemical and immunocytochemical assessment of our perspective on this intimate cellular interaction which has been described recently in conditions that involve immunological alterations of the BBB. We will discuss some morphological aspects of what is currently known about acute and chronic inflammatory BBB disorders that are involved in inflammatory processes. We will focus, in particular, on experimental allergic encephalomyelitis (EAE), an animal model for human multiple sclerosis (MS). Many of the past and more recent concepts found in the literature concerning IC attachment and diapedesis, as well as our own experimental efforts over more than two decades will be presented.
DOI: 10.1016/0026-2862(90)90037-r
发表时间: 1990
影响因子: 3.1
作者:
Lossinsky,AS;Song,MJ;Pluta,R;Moretz,RC;Wisniewski,HM
通讯作者: Wisniewski,HM
DOI: --
发表时间: 1987
期刊: The American journal of pathology
影响因子: --
作者:
Cotran,RS
通讯作者: Cotran,RS
DOI: 10.4049/jimmunol.142.10.3416
发表时间: 1989-05
影响因子: 4.4
作者:
D. Willerford;P. Hoffman;W. Gallatin
通讯作者: D. Willerford;P. Hoffman;W. Gallatin
慢性复发性实验性过敏性脑脊髓炎炎症细胞附着机制:对受损小鼠血脑屏障的扫描和高压电子显微镜研究。
DOI: 10.1016/0026-2862(91)90030-f
发表时间: 1991
影响因子: 3.1
作者:
Lossinsky,AS;Pluta,R;Song,MJ;Badmajew,V;Moretz,RC;Wisniewski,HM
通讯作者: Wisniewski,HM
DOI: --
发表时间: 1989-12
期刊: The American journal of pathology
影响因子: --
作者:
L. Claudio;Y. Kress;W. T. Norton;C. Brosnan
通讯作者: L. Claudio;Y. Kress;W. T. Norton;C. Brosnan