OSTEOARTHRITIS OF THE HIP AND OCCUPATIONAL ACTIVITY
OSTEOARTHRITIS OF THE HIP AND OCCUPATIONAL ACTIVITY
复制标题
DOI：
10.5271/sjweh.1608
复制
发表时间：
1992-02-01
影响因子：
6.3
通讯作者：
COGGON, D
中科院分区：
文献类型：
--
作者：
CROFT, P;COOPER, C;COGGON, D
本病例对照研究探讨髋关节骨关节炎与职业活动的关系。受试者为60- 75岁男性，接受过静脉尿路造影。对245例因骨关节炎或关节间隙≤ 2.5mm行髋关节置换术的患者和294例双侧关节间隙≥ 3.5mm的参考者进行了访谈。在对所有病例的分析中没有发现明显的相关性，但严重疾病（骨关节炎髋关节置换术或关节间隙小于或等于1.5 mm）在农民中更常见，特别是在那些从事农业工作超过或等于10年的人中[比值比（OR）2.0，95%置信区间（95%CI）0.9-4.4]。重度疾病还与长时间站立工作（OR 2.7，95% CI 1.0-7.3）和举重（OR 2.5，95% CI 1.1-5.7）相关。这些关联不能用肥胖或体育活动来解释。研究结果表明，农民患退行性髋关节疾病的风险增加，并表明机械超载可能有助于其发病机制。
This case-referent study investigated the relation between hip osteoarthritis and occupational activity. The subjects were 60- to 75-year-old men who had undergone intravenous urography. Interviews were obtained for 245 cases who had a hip replacement for osteoarthritis or a joint space of less-than-or-equal-to 2.5 mm and 294 referents whose joint space was greater-than-or-equal-to 3.5 mm in both hips. No clear associations were found in an analysis of all the cases, but severe disease (hip replacement for osteoarthritis or a joint space of less-than-or-equal-to 1.5 mm) was more common in the farmers, especially in those with greater-than-or-equal-to 10 years in agricultural work [odds ratio (OR) 2.0, 95% confidence interval (95% CI) 0.9-4.4]. Severe disease was also associated with prolonged standing at work (OR 2.7, 95% CI 1.0-7.3) and heavy lifting (OR 2.5, 95% CI 1.1-5.7). These associations could not be explained by obesity or sporting activity. The findings suggest an increased risk of degenerative hip disease for farmers and indicate that mechanical overloading may contribute to its pathogenesis.