Functional dyspepsia: The role of visceral hypersensitivity in its pathogenesis
Functional dyspepsia: The role of visceral hypersensitivity in its pathogenesis
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DOI：
10.3748/wjg.v12.i17.2672
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发表时间：
2006-05-07
影响因子：
4.3
通讯作者：
Quigley, Eamonn M. M.
中科院分区：
文献类型：
--
作者：
Keohane, John;Quigley, Eamonn M. M.
功能性或非溃疡性消化不良(FD)是转诊至胃肠病科医生的最常见原因之一。它与严重的发病率和生活质量受损有关。许多权威人士认为，功能性消化不良和肠易激综合征是同一疾病过程的一部分。FD的病理生理机制尚不清楚，但已有多种学说被提出，包括内脏高敏感性、胃运动功能障碍、幽门螺杆菌感染和心理社会因素。在这篇综述中，我们着眼于迄今为止内脏高敏感性在FD病因学中的作用的证据。(C)2006年WJG出版社。版权所有。
Functional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD. (C) 2006 The WJG Press. All rights reserved.