Premature coronary artery disease: clinical risk factors and prognosis.
Premature coronary artery disease: clinical risk factors and prognosis.
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DOI：
10.1007/s11883-004-0100-z
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发表时间：
2004-03-01
影响因子：
5.8
通讯作者：
Sperling, Laurence S
中科院分区：
文献类型：
--
作者：
Cole, Jason H;Sperling, Laurence S
年轻人中出现的冠状动脉疾病（CAD）可能会产生毁灭性的后果。此外，对年轻 CAD 患者的研究可能有助于深入了解冠心病的遗传基础。在过去的几年里，我们对这一人群风险因素的理解已经扩大到包括社会、环境和情感因素。疾病遗传标记的识别才刚刚开始。此外，最近的研究表明，年轻人的 CAD 长期预后较差，这意味着护理这些患者的临床医生必须积极控制危险因素。
Coronary artery disease (CAD) that becomes manifest in young adults can have devastating consequences. Additionally, the study of young patients with CAD may provide insight into the genetic basis of coronary disease. Over the past few years, our understanding of risk factors in this population has been expanded to include social, environmental, and emotional factors. The identification of genetic markers for disease is just beginning. Also, it has recently been shown that CAD in young adults has a poor long-term prognosis, meaning that clinicians caring for these patients must be aggressive in risk factor control.