Diabetic foot ulcers Part I. Pathophysiology and prevention

Diabetic foot ulcers Part I. Pathophysiology and prevention
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DOI:
10.1016/j.jaad.2013.06.055
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发表时间:
2014-01-01
影响因子:
13.8
通讯作者:
Kirsner, Robert S.
Kirsner, Robert S.
中科院分区:
医学1区
文献类型:
--
作者:
Alavi, Afsaneh;Sibbald, R. Gary;Kirsner, Robert S.

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糖尿病是一种严重的终生疾病,在北美是第六大死亡原因。皮肤科医生经常会遇到糖尿病患者。高达25%的糖尿病患者会发展成糖尿病足部溃疡。足部溃疡患者截肢的风险和死亡率都会增加。可以通过简化的筛查来识别高危糖尿病足,并可以预防后续的足部溃疡。及早认识高危足病,及时治疗,保住双腿,提高患者生活质量。周围动脉病变、神经病变、畸形、既往截肢和感染是导致糖尿病足部溃疡的主要因素。早期认识高危足病是降低死亡率和发病率的关键。通常需要跨专业的方法(即医生、护士和足部护理专家)来支持患者的需求。
Diabetes mellitus is a serious, life-long condition that is the sixth leading cause of death in North America. Dermatologists frequently encounter patients with diabetes mellitus. Up to 25% of patients with diabetes mellitus will develop diabetic foot ulcers. Foot ulcer patients have an increased risk of amputation and increased mortality rate. The high-risk diabetic foot can be identified with a simplified screening, and subsequent foot ulcers can be prevented. Early recognition of the high-risk foot and timely treatment will save legs and improve patients' quality of life. Peripheral arterial disease, neuropathy, deformity, previous amputation, and infection are the main factors contributing to the development of diabetic foot ulcers. Early recognition of the high-risk foot is imperative to decrease the rates of mortality and morbidity. An interprofessional approach (ie, physicians, nurses, and foot care specialists) is often needed to support patients' needs.