Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes -: A Randomized trial
Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes -: A Randomized trial
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DOI：
10.7326/0003-4819-147-6-200709180-00005
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发表时间：
2007-09-18
影响因子：
39.2
通讯作者：
Jaffey, James
中科院分区：
文献类型：
--
作者：
Sigal, Ronald J.;Kenny, Glen P.;Jaffey, James
背景资料：之前的试验评估了单独有氧训练和单独阻力训练对2型糖尿病血糖控制的影响，通过血红蛋白A（1c）值进行评估。然而，没有人能够评估有氧和阻力训练相结合的增量效果与单独的任何一种类型的exercises.Objective：为了确定有氧训练单独，阻力训练单独，和结合运动训练对2型糖尿病患者血红蛋白A（1c）值的影响。设计：随机对照试验。设置：8个社区为基础的设施。患者：2151例年龄在39至70岁之间的2型糖尿病患者。在随机化之前，要求心脏病专家的压力测试或清除结果为阴性，并且在4周的导入期内坚持锻炼。干预措施：有氧训练，阻力训练，或两种类型的运动（联合运动训练）。包括久坐的对照组。每周进行3次运动训练，持续22周（研究的第5至26周）。次要结果是身体成分、血脂值和血压的变化。综合运动训练组与对照组相比，血红蛋白A值的绝对变化为-0.51个百分点（95%CI，-0.87 ~-0.14），阻力训练组为-0.38个百分点（CI，-0.72 ~-0.22）。与单独有氧训练相比，联合运动训练导致血红蛋白A值的额外变化为-0.46个百分点（Cl，-0.83至-0.09），与单独阻力训练相比为-0.59个百分点（Cl，-0.95至-0.23）。各组之间血压和血脂值的变化无统计学显著差异。不良事件在运动组中更为常见。局限性：结果对那些不太坚持运动计划的患者的普遍性是不确定的。参与者没有盲目的，运动的总持续时间是更大的运动训练组比在有氧和阻力training groups.Conclusion：无论是有氧或阻力训练单独提高血糖控制在2型糖尿病，但改善是最大的有氧和阻力训练相结合。
Background: Previous trials have evaluated the effects of aerobic training alone and of resistance training alone on glycemic control in type 2 diabetes, as assessed by hemoglobin A(1c) values. However, none could assess incremental effects of combined aerobic and resistance training compared with either type of exercise alone.Objective: To determine the effects of aerobic training alone, resistance training alone, and combined exercise training on hemoglobin A(1c) values in patients with type 2 diabetes.Design: Randomized, controlled trial.Setting: 8 community-based facilities.Patients: 2151 adults age 39 to 70 years with type 2 diabetes. A negative result on a stress test or clearance by a cardiologist, and adherence to exercise during a 4-week run-in period, were required before randomization.Interventions: Aerobic training, resistance training, or both types of exercise (combined exercise training). A sedentary control group was included. Exercise training was performed 3 times weekly for 22 weeks (weeks 5 to 26 of the study).Measurements: The primary outcome was the change in hemoglobin A,, value at 6 months. Secondary outcomes were changes in body composition, plasma lipid values, and blood pressure.Results: The absolute change in the hemoglobin A, value in the combined exercise training group compared with the control group was -0.51 percentage point (95% Cl, -0.87 to -0.14) in the aerobic training group and -0.38 percentage point (Cl, -0.72 to -0.22) in the resistance training group. Combined exercise training resulted in an additional change in the hemoglobin A, value of -0.46 percentage point (Cl, -0.83 to -0.09) compared with aerobic training alone and -0.59 percentage point (Cl, -0.95 to -0.23) compared with resistance training alone. Changes in blood pressure and lipid values did not statistically significantly differ among groups. Adverse events were more common in the exercise groups.Limitations: The generalizability of the results to patients who are less adherent to exercise programs is uncertain. The participants were not blinded, and the total duration of exercise was greater in the combined exercise training group than in the aerobic and resistance training groups.Conclusion: Either aerobic or resistance training alone improves glycemic control in type 2 diabetes, but the improvements are greatest with combined aerobic and resistance training.