Type III secretion system effector proteins are mechanically labile
Type III secretion system effector proteins are mechanically labile
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DOI：
10.1073/pnas.2019566118
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发表时间：
2021-03-23
影响因子：
11.1
通讯作者：
Sousa, Marcelo C.
中科院分区：
文献类型：
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作者：
Leblanc, Marc-Andre;Fink, Morgan R.;Sousa, Marcelo C.
多种革兰氏阴性细菌编码III型分泌系统（T3SS），其允许它们将效应蛋白直接注射到宿主细胞中以促进定殖。为了分泌，效应蛋白必须至少部分解折叠以通过狭窄的针状通道（直径
Multiple gram-negative bacteria encode type III secretion systems (T3SS) that allow them to inject effector proteins directly into host cells to facilitate colonization. To be secreted, effector proteins must be at least partially unfolded to pass through the narrow needle-like channel (diameter