Different patterns of circadian oscillation in the suprachiasmatic nucleus of hamster, mouse, and rat
Different patterns of circadian oscillation in the suprachiasmatic nucleus of hamster, mouse, and rat
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DOI：
10.1007/s00359-003-0486-z
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发表时间：
2004-02-01
影响因子：
2.1
通讯作者：
Gillette, MU
中科院分区：
文献类型：
--
作者：
Burgoon, PW;Lindberg, PT;Gillette, MU
虽然哺乳动物视交叉上核中的自发神经放电被接受为在主观的一天中达到一次峰值，但是在取自仓鼠的水平脑切片中已经报道了双活动峰值。这两个峰值被解释为双昼夜节律振荡器理论的新证据，并提出了在其他昼夜节律模型系统中发现这种活动的期望。我们研究了仓鼠，小鼠和大鼠切片的冠状面和水平面，发现只有在仓鼠水平的准备活动的第二个高峰。这提出了关于这些重要实验动物的相对昼夜生理的有趣问题。
Although spontaneous neural firing in the mammalian suprachiasmatic nucleus is accepted to peak once during mid-subjective day, dual activity peaks have been reported in horizontal brain slices taken from hamsters. These two peaks were interpreted as new evidence for the theory of dual circadian oscillators and raised the expectation that such activity would be found in other circadian model systems. We examined hamster, mouse, and rat slices in both coronal and horizontal planes and found a second peak of activity only in hamster horizontal preparations. This raises interesting questions about the relative circadian physiology of these important experimental animals.