Cortical-limbic mechanisms and response control: A theoretical review
Cortical-limbic mechanisms and response control: A theoretical review
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皮质边缘机制和反应控制：理论回顾
DOI：
10.3758/bf03326750
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
R. Numan
中科院分区：
文献类型：
--
作者：
R. Numan
本文综述了有关隔区、额叶皮质区和海马损伤对行为影响的文献。它的结论是，背内侧隔，背外侧额叶皮质（和同源结构），背海马形成一个节点内的一个更大的神经元系统，参与反应调节。提出了一个模型，描述这个额叶皮质边缘系统介导的反应调节过程。运动程序写在额叶皮层，暂时存储在海马体。来自反应启动和维护的反馈刺激与存储的海马运动程序进行比较。如果反馈信息与由运动程序指示的预期结果匹配，则响应序列终止。如果比较器出现偏差，额叶皮层区域就会发出错误信号，并编写新的运动程序。假设海马theta活动与比较器激活和反馈分析相关。
The literature dealing with the behavioral effects produced by lesions of the septum, frontal cortical areas, and the hippocampus is reviewed. It is concluded that the dorsomedial septum, the dorsolateral frontal cortex (and homologous structures), and the dorsal hippocampus form a nodal point within a larger neuronal system that is involved in response regulation. A model describing the response regulatory processes mediated by this frontal cortical-limbic system is proposed. Motor programs are written in frontal cortex and temporarily stored in hippocampus. Feedback stimuli derived from response initiation and maintenance are compared against the stored hippocampal motor program. If the feedback information matches with the expected outcomes dictated by the motor program, the response sequence is terminated. If comparator deviations arise, the frontal cortical areas are signaled of error and a new motor program is written. Hippocampal theta activity is postulated to be a correlate of comparator activation and feedback analysis.