Carcinosarcoma of the gallbladder: report of two cases
Carcinosarcoma of the gallbladder: report of two cases
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DOI：
10.1007/s00595-012-0160-6
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发表时间：
2012-07-01
期刊：
影响因子：
2.5
通讯作者：
Cho, Chol Kyoon
中科院分区：
文献类型：
--
作者：
Kim, Ho-Hyun;Hur, Young-Hoe;Cho, Chol Kyoon
腺癌是胆囊癌的主要组织学类型，占所有胆囊癌的80%以上。相比之下，胆囊癌肉瘤是胆囊恶性肿瘤的一个非常不典型的子集。其特征在于上皮和间充质成分的存在。目前，在英国文献中报告的病例不到100例。因此，关于这种疾病的知识和经验有限。最近，我们经历了两例胆囊癌肉瘤，根据术前临床和放射学检查，诊断为胆囊癌。两例病例均行胆囊切除术，组织学检查恶性肿瘤细胞包括癌性成分和肉瘤成分。最后病理诊断为胆囊癌肉瘤。我们在此报告这两个胆囊癌肉瘤的病例，并回顾以往的相关文献。
Adenocarcinoma is the predominant histological type of carcinoma of the gallbladder, accounting for more than 80% of all gallbladder carcinomas. In contrast, carcinosarcoma of the gallbladder is an extremely atypical subset of gallbladder malignancies. It is characterized by the presence of both epithelial and mesenchymal components. Currently, fewer than 100 cases have been reported in the English literature. Therefore, knowledge and experience regarding this disease are limited. Recently, we experienced two cases of gallbladder carcinosarcoma, which were diagnosed as gallbladder carcinoma based on the preoperative clinical and radiological examinations. Cholecystectomies were performed in both cases, and the malignant tumor cells included carcinomatous and sarcomatous components histologically. The final pathological diagnoses were carcinosarcoma of the gallbladder. We herein report these two cases of gallbladder carcinosarcoma and review the previous pertinent literature.