Optimization of Chiral Structures for Microscale Propulsion
Optimization of Chiral Structures for Microscale Propulsion
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DOI：
10.1021/nl3040477
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发表时间：
2013-02-01
期刊：
影响因子：
10.8
通讯作者：
Shelley, Michael J.
中科院分区：
文献类型：
--
作者：
Keaveny, Eric E.;Walker, Shawn W.;Shelley, Michael J.
微纳米级制造技术的最新进展允许构建刚性的、螺旋形的微游泳器，这些微游泳器可以使用外加磁场驱动。这些游泳者代表了用于靶向药物输送和微创外科手术的微型机器人发展的第一步。为了评估这些设备的性能并改进其设计，我们进行了形状优化计算，以确定在给定施加磁扭矩的方向上最大速度的游泳器几何形状。我们直接评估了先前实验研究中开发的游泳者形状的各个方面，包括具有细长截面和附加有效载荷的螺旋螺旋桨。通过这些优化，我们确定了对现有设计的关键改进，从而使游泳速度达到原始值的70-470%。
Recent advances in micro- and nanoscale fabrication techniques allow for the construction of rigid, helically shaped microswimmers that can be actuated using applied magnetic fields. These swimmers represent the first steps toward the development of microrobots for targeted drug delivery and minimally invasive surgical procedures. To assess the performance of these devices and improve on their design, we perform shape optimization computations to determine swimmer geometries that maximize speed in the direction of a given applied magnetic torque. We directly assess aspects of swimmer shapes that have been developed in previous experimental studies, including helical propellers with elongated cross sections and attached payloads. From these optimizations, we identify key improvements to existing designs that result in swimming speeds that are 70-470% of their original values.