[Blue light source in phototherapy]

[Blue light source in phototherapy]
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【光疗中的蓝光光源】

DOI:
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发表时间:
2002
影响因子:
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通讯作者:
L. Du
L. Du
中科院分区:
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文献类型:
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作者:
C. Zhang;Jue Wang;L. Du

文献摘要

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目的:探讨蓝色发光二极管(LED)作为新型光疗光源的功效。方法:用两个光源照射等摩尔胆红素标准白蛋白溶液; LED 和单面传统蓝光 (sCBL)。用照度计测量光强度。 LED 的发射强度与 sCBL 相同。为了评估两种光源的效果,使用高效液相色谱法测定了光疗之前和期间胆红素异构体的变化。结果:不同光源对等摩尔胆红素标准白蛋白溶液、LEDs的鲁米红素(LR)和4Z、15E-胆红素IX α(ZE)形成的影响与sCBL相同(P>0.05)。结论:对于体外光疗,LED 与单一 sCBL 同等有效。
OBJECTIVE: To explore the efficacy of blue light-emitting diodes(LEDs) as a novel light source for phototherapy. METHODS: Equimolar bilirubin standard albumin solutions were irradiated with two light sources; LEDs and single side conventional blue light( sCBL). Light intensity was measured with a light meter. The emission intensity of LEDs was the same as sCBL. To estimate the effects of the two light sources, the change in bilirubin isomer before and during phtotherapy was determined using high-performance liquid chromatography. RESULTS: The effects of different light sources on equimolar bilirubin standard albumin solutions, the lumirubin (LR) and 4Z, 15E-Bilirubin IX alpha(ZE) formation of LEDs was the same as sCBL(P>0.05). CONCLUSION: LEDs is equally effective as single sCBL for phototherapy in vitro.