Relation of degree of physical activity to coronary artery calcium score in asymptomatic individuals with multiple risk factors

Relation of degree of physical activity to coronary artery calcium score in asymptomatic individuals with multiple risk factors
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DOI:
10.1016/j.amjcard.2004.06.004
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发表时间:
2004-09-15
影响因子:
2.8
通讯作者:
Blumenthal, RS
Blumenthal, RS
中科院分区:
医学3区
文献类型:
--
作者:
Desai, MY;Nasir, K;Blumenthal, RS

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Lack of physical activity (PA) increases risk of coronary heart disease. Metabolic risk factors increase the risk of coronary heart disease and development of advanced coronary artery calcium (CAC). We hypothesized that, in a population with multiple metabolic risk factors ( greater than or equal to2), the degree of PA would be inversely associated with the degree and prevalence of CAC. After excluding subjects who had known diabetes and coronary heart disease, we studied 779 asymptomatic patients referred for electron beam tomography. All patients had greater than or equal to2 of the following metabolic risk factors: blood pressure > 130/85 mm Hg, serum triglycerides > 150 mg/dl, serum high-density lipoprotein 75th percentile based on gender and age. In the study, 37% patients were sedentary, 26% engaged in moderate-duration (