Ganglioneuroma of the internal auditory canal: A case report

Ganglioneuroma of the internal auditory canal: A case report
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DOI:
10.1159/000099018
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发表时间:
2007-01-01
影响因子:
1.6
通讯作者:
Erdogan, Bulent
Erdogan, Bulent
中科院分区:
医学3区
文献类型:
--
作者:
Ozluoglu, Levent Naci;Yilmaz, Ismail;Erdogan, Bulent

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神经节神经瘤是一种罕见的、良性的、生长缓慢的肿瘤,被认为是从神经嵴起源的细胞发展而来的,尽管关于这种病变的发病机制的假说不同。神经节神经瘤不释放过量的儿茶酚胺或类固醇激素,主要发生在后纵隔和腹膜后。由于生长缓慢,许多神经节神经瘤在确诊时很大。在这个病例报告中,描述了一个50岁的听力损失妇女。磁共振成像显示内耳道(IAC)肿块(3 x 4 mm)。经中窝入路完全切除包膜肿瘤。组织病理学检查结果显示,切除病变为神经节神经瘤。据我们所知,这是第一个关于IAC神经节神经瘤的报道。我们建议在IAC所有肿瘤的鉴别诊断中应考虑神经节神经瘤。版权所有(C) 2007 S. Karger AG,巴塞尔
Ganglioneuroma is a rare, benign, slow-growing tumor thought to develop from cells of neural crest origin, even though hypotheses on the pathogenesis of that lesion differ. Ganglioneuromas, which do not release excessive catecholamine or steroid hormones, develop primarily in the posterior mediastinum and retroperitoneum. Because of their slow growth, many ganglioneuromas are large when they are diagnosed. In this case report, a 50-year-old woman with hearing loss is described. Magnetic resonance imaging revealed a mass (3 x 4 mm) in the internal auditory canal (IAC). The encapsulated tumor was entirely excised via the middle fossa approach. The results of histopathological examination indicated that the excised lesion was a ganglioneuroma. To our knowledge, this is the first report of a ganglioneuroma of the IAC. We suggest that ganglioneuroma be considered in the differential diagnosis of all tumors of the IAC. Copyright (C) 2007 S. Karger AG, Basel.