New respiratory viruses and the elderly.
New respiratory viruses and the elderly.
复制标题
新呼吸道病毒与老年人。
DOI：
10.2174/1874306401105010061
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Jartti T
中科院分区：
文献类型：
--
作者：
Jartti L;Langen H;Söderlund-Venermo M;Vuorinen T;Ruuskanen O;Jartti T
在过去的15年中，随着PCR技术的发展，呼吸道病毒感染的诊断得到了显著改善。自1997年以来，已经发现了几种新的呼吸道病毒及其亚群：A型流感病毒H5N1和H1N1、人偏肺病毒、冠状病毒SARS、NL 63和HKU1、人博卡病毒、人鼻病毒C和D以及潜在的呼吸道病原体、KI和WU多瘤病毒和细环扭体病毒。对以前已知病毒的检测也有所改进。目前，呼吸道疾病的病毒病因几乎仅在儿童中可识别，但在老年人中，病毒病因的检出率低于40%，这也适用于慢性呼吸道疾病的恶化。新病毒引起呼吸道症状，如普通感冒，咳嗽，支气管炎，细支气管炎，哮喘和慢性阻塞性肺病和肺炎的恶化。可能发生急性呼吸衰竭。这些病毒遍布地球仪，影响所有年龄段的人。关于这些病毒和老年人的数据很少。本文介绍了这些新的病毒，并审查其临床意义，特别是关于老年人口。
The diagnostics of respiratory viral infections has improved markedly during the last 15 years with the development of PCR techniques. Since 1997, several new respiratory viruses and their subgroups have been discovered: influenza A viruses H5N1 and H1N1, human metapneumovirus, coronaviruses SARS, NL63 and HKU1, human bocavirus, human rhinoviruses C and D and potential respiratory pathogens, the KI and WU polyomaviruses and the torque teno virus. The detection of previously known viruses has also improved. Currently, a viral cause of respiratory illness is almost exclusively identifiable in children, but in the elderly, the detection rates of a viral etiology are below 40%, and this holds also true for exacerbations of chronic respiratory illnesses. The new viruses cause respiratory symptoms like the common cold, cough, bronchitis, bronchiolitis, exacerbations of asthma and chronic obstructive pulmonary disease and pneumonia. Acute respiratory failure may occur. These viruses are distributed throughout the globe and affect people of all ages. Data regarding these viruses and the elderly are scarce. This review introduces these new viruses and reviews their clinical significance, especially with regard to the elderly population.