STRUCTURE OF ALPHA-ALPHA-HAIRPINS WITH SHORT CONNECTIONS
STRUCTURE OF ALPHA-ALPHA-HAIRPINS WITH SHORT CONNECTIONS
复制标题
DOI：
10.1093/protein/4.3.245
复制
发表时间：
1991-02-01
期刊：
影响因子：
--
通讯作者：
EFIMOV, AV
中科院分区：
文献类型：
--
作者：
EFIMOV, AV
本文对短连接的α-α-发夹的结构和序列进行了详细的立体化学分析。结果表明，每种类型的α-发夹在其氨基酸序列中都具有非常相似的疏水、亲水和甘氨酸残基模式。这些结果可用于预测α-α-发夹构象，也可用于蛋白质设计和工程。
This paper presents the results of detailed stereochemical analysis of structures and sequences of alpha-alpha-hairpins with short connections. It is shown that alpha-alpha-hairpins of each given type have very similar patterns of hydrophobic, hydrophilic and glycine residues in their amino acid sequences. These results can be used in the prediction of alpha-alpha-hairpin conformation as well as in protein design and engineering.