EFFECTS OF ACTIVATION SEQUENCE ON LOCAL RECOVERY OF VENTRICULAR EXCITABILITY IN DOG
EFFECTS OF ACTIVATION SEQUENCE ON LOCAL RECOVERY OF VENTRICULAR EXCITABILITY IN DOG
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DOI：
10.1161/01.res.38.4.240
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发表时间：
1976-01-01
影响因子：
20.1
通讯作者：
ABILDSKOV, JA
中科院分区：
文献类型：
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作者：
ABILDSKOV, JA
我们测量了从心室测试部位驱动期间以及从测试部位和其他心室部位或心房联合驱动期间狗心脏心室部位的不应期。我们发现心室激动序列引起不应期的显着改变。来自两个部位的联合驱动导致融合复合物，与仅在测试部位驱动期间观察到的不应期相比，在测试部位处与更短的不应期相关。我们的发现是可以解释的，因为融合节拍期间周围区域的早期激发和随后的早期恢复会对测试部位产生电紧张影响。
We measured refractory periods at ventricular sites in the dog heart during drive from ventricular test sites and during combined drive from the test sites and other ventricular sites or the atrium. We found that ventricular activation sequence caused significant alterations on refractory period. Combined drive from two sites which resulted in fusion complexes was associated with shorter refractory periods at the test sites than those observed during drive at the test sites only. Our findings are explicable because earlier excitation and consequent earlier recovery of surrounding areas during fusion beats exerts an electrotonic influence on test sites.