PARTICULATE AIR-POLLUTION AND HOSPITAL EMERGENCY ROOM VISITS FOR ASTHMA IN SEATTLE
PARTICULATE AIR-POLLUTION AND HOSPITAL EMERGENCY ROOM VISITS FOR ASTHMA IN SEATTLE
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DOI：
10.1164/ajrccm/147.4.826
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发表时间：
1993-04-01
期刊：
影响因子：
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通讯作者：
KOENIG, JQ
中科院分区：
文献类型：
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作者：
SCHWARTZ, J;SLATER, D;KOENIG, JQ
最近的研究表明，短期暴露于可吸入颗粒物（PM10）与峰值流量下降、呼吸道刺激症状增加、哮喘药物使用增加和哮喘住院治疗增加有关。据报告，慢性呼吸道疾病的死亡率也有所增加。为了帮助确认PM10暴露是否是哮喘恶化的危险因素，我们收集了西雅图地区八家医院哮喘急诊室的每日就诊记录。在控制天气，季节，时间趋势，年龄，医院和一周中的一天的泊松回归中，65岁以下的人每天急诊室就诊次数与前一天的PM10暴露显著相关。前4天的PM10均值是较好的预测因子（p < 0.005）。PM10增加30 mug/m3的相对风险为1.12（95%置信区间为1.20至1.04）。在此期间，每日PM10浓度从未超过现行环境空气质量标准的70%。PM10对健康影响的调查的一致性表明，应更加重视颗粒物空气污染的控制。
Recent studies have associated short-term exposure to respirable particulate matter (PM10) exposure with peak flow decrements, increased symptoms of respiratory irritation, increased use of asthma medications, and increased hospitalization for asthma. Increased mortality from chronic respiratory disease has also been reported. To help confirm whether PM10 exposure is a risk factor for the exacerbation of asthma, we compiled daily records of asthma emergency room visits from eight hospitals in the Seattle area. In Poisson regressions controlling for weather, season, time trends, age, hospital, and day of the week, the daily counts of emergency room visits for persons under age 65 were significantly associated with PM10 exposure on the previous day. The mean of the previous 4 days' PM10 was a better predictor (p < 0.005). The relative risk for a 30 mug/m3 increase in PM10 was 1.12 (95% confidence interval 1.20 to 1.04). Daily PM10 concentrations never exceeded 70% of the current ambient air quality standards during the period. The consistency of investigations of the health effects of PM10 suggest that increased attention should be given to the control of particulate matter air pollution.