Workshop report: The medaka model for comparative assessment of human disease mechanisms.
Workshop report: The medaka model for comparative assessment of human disease mechanisms.
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DOI：
10.1016/j.cbpc.2015.06.003
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发表时间：
2015-12
期刊：
影响因子：
--
通讯作者：
Obara T
中科院分区：
文献类型：
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作者：
Walter RB;Obara T
最近的研究结果显示青鳉作为各种人类疾病状态的模型的效用在第七届人类疾病水生模型会议（2014年12月13日至18日，德克萨斯州奥斯汀）上发表。这次会议汇集了许多最受尊敬的国家和国际科学家，他们在调查中采用了青斑模型。为了利用这一机会，一批已建立的青鳉研究人员被要求多呆一天，代表青鳉科学界参加一个题为“青鳉人类疾病机制比较评估模型”的讲习班。这次青鳉研讨会的中心目的是评估美国青鳉研究界目前的使用情况，并预测未来的资源需求。讲习班力求推动对一些问题的讨论，以促进信息量更大的比较疾病模型研究。最后，研讨会与会者聚集在一起，提出、讨论并商定了有关最有效的研究资源的建议，这些资源使美国科学家能够进行实验，从而影响直接转化为人类疾病的实验结果。根据这一中心目标，讲习班分为两场会议，邀请在会议专题方面具有专门知识和经验的发言者参加。研讨会接待了20名科学参与者（附录1和2），其中9名科学家进行了正式会谈。在这里，我们提出了一个总结报告，来自研讨会的介绍和随后的圆桌会议讨论，并提出建议，我们认为这组代表了整个青鳉研究界的意见。
Results of recent studies showing the utility of medaka as a model of various human disease states were presented at the 7th Aquatic Models of Human Disease Conference (December 13–18, 2014, Austin, TX). This conference brought together many of the most highly regarded national and international scientists that employ the medaka model in their investigations. To take advantage of this opportunity, a cohort of established medaka researchers were asked to stay an extra day and represent the medaka scientific community in a workshop entitled “The Medaka Model for Comparative Assessment of Human Disease Mechanisms”. The central purpose of this medaka workshop was to assess current use and project the future resource needs of the American medaka research community. The workshop sought to spur discussions of issues that would promote more informative comparative disease model studies. Finally, workshop attendees met together to propose, discuss, and agree on recommendations regarding the most effective research resources needed to enable US scientists to perform experiments leading to impacting experimental results that directly translate to human disease. Consistent with this central purpose, the workshop was divided into two sessions of invited speakers having expertise and experience in the session topics. The workshop hosted 20 scientific participants (Appendices 1 and 2) and of these, nine scientists presented formal talks. Here, we present a summary report stemming from workshop presentations and subsequent round table discussions, and forward recommendations from this group that we believe represent views of the overall medaka research community.