High‐concentration cultivation of Lactococcus cremoris in a cell‐recycle reactor
High‐concentration cultivation of Lactococcus cremoris in a cell‐recycle reactor
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DOI：
10.1002/bit.260370809
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发表时间：
1991-04
影响因子：
3.8
通讯作者：
Bernard Bibal;Y. Vayssier;G. Goma;A. Pareilleux
中科院分区：
文献类型：
--
作者：
Bernard Bibal;Y. Vayssier;G. Goma;A. Pareilleux
High‐cell concentration cultivation of Lactococcus cremoris, a homofermentative lactic acid producer, in a cell‐recycle fermentor is described. Cross‐flow filtration allowing continuous removal of the inhibitory metabollte, the influence of dilution rate on growth was investigated in total or partial cell‐recycle cultures. The dependence of growth characteristics on operating conditions was identified and quantified using lactose as the carbon source. Growth kinetics could be described by both lactate removal efficiency and nutrient availability. Based on physiological observations, biomass and lactic acid productivities were predicted in partial cell‐recycle cultures.
