Residential agricultural pesticide exposures and risks of preeclampsia.
Residential agricultural pesticide exposures and risks of preeclampsia.
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DOI：
10.1016/j.envres.2018.03.020
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发表时间：
2018-07
影响因子：
8.3
通讯作者：
English PB
中科院分区：
文献类型：
--
作者：
Shaw GM;Yang W;Roberts EM;Aghaeepour N;Mayo JA;Weber KA;Maric I;Carmichael SL;Winn VD;Stevenson DK;English PB
我们调查了潜在居民农药暴露导致先兆子痫表型的风险，包括1998-2011年研究期间在加州圣华金河谷应用的543种化学品和69种理化分组。研究人群来源于出生证明数据与全州卫生规划和发展办公室孕产妇和婴儿出院数据。确定了以下数量的具有先兆子痫表型的妇女：先兆子痫（preeclampsia）（265例妊娠20-31周，780例妊娠32-36周）; 3471例重度先兆子痫（824例妊娠20-31周，2647例妊娠32-36周）; 2780例轻度先兆子痫（207例妊娠20-31周，2573例妊娠32-36周）。这些组的参考人群是197，461名没有糖尿病（妊娠期或预先存在），没有任何高血压疾病，并且在37周或更晚分娩的女性。相对于参考人群对照组的频率，每个先兆子痫病例组（进一步按胎龄描述）和月时间段的任何暴露频率均较低或大致相同。几乎所有的比值比都低于1.0，这些任何与无暴露比较。这项研究表明，妇女住所附近的一系列农业农药暴露与各种先兆子痫表型之间的风险普遍缺乏增加。
We investigated risks of preeclampsia phenotypes from potential residential pesticide exposures, including 543 individual chemicals and 69 physicochemical groupings that were applied in the San Joaquin Valley of California during the study period, 1998–2011. The study population was derived from birth certificate data linked with Office of Statewide Health Planning and Development maternal and infant hospital discharge data. The following numbers of women with preeclampsia phenotypes were identified: 1045 with superimposed (pre-existing hypertension with preeclampsia) preeclampsia (265 with gestational weeks 20–31 and 780 with gestational weeks 32–36); 3471 with severe preeclampsia (824 with gestational weeks 20–31 and 2647 with gestational weeks 32–36); and 2780 with mild preeclampsia (207 with gestational weeks 20–31 and 2573 with gestational weeks 32–36). The reference population for these groups was 197,461 women who did not have diabetes (gestational or pre-existing), did not have any hypertensive disorder, and who delivered at 37 weeks or later. The frequency of any exposure was lower or about the same in each preeclampsia case group (further delineated by gestational age), and month time period, relative to the frequency in reference population controls. Nearly all odds ratios were below 1.0 for these any vs no exposure comparisons. This study showed a general lack of increased risks between a range of agriculture pesticide exposures near women’s residences and various preeclampsia phenotypes.
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影响因子：
11.8
作者：
Rosenbaum PF;Weinstock RS;Silverstone AE;Sjödin A;Pavuk M
通讯作者：
Pavuk M
影响因子：
3.7
作者：
Nugteren JJ;Snijder CA;Hofman A;Jaddoe VW;Steegers EA;Burdorf A
通讯作者：
Burdorf A
影响因子：
5.4
作者：
Kinlaw, Alan C.;Buckley, Jessie P.;Keil, Alexander P.
通讯作者：
Keil, Alexander P.
影响因子：
2.8
作者：
Siddiqui, MKJ;Nigam, U;Chandrawati
通讯作者：
Chandrawati
DOI：
10.3109/14767058.2012.710280
发表时间：
2012-12
期刊：
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
影响因子：
--
作者：
Lyndon A;Lee HC;Gilbert WM;Gould JB;Lee KA
通讯作者：
Lee KA