VENTRAL INTRAPARIETAL AREA OF THE MACAQUE - ANATOMIC LOCATION AND VISUAL RESPONSE PROPERTIES
VENTRAL INTRAPARIETAL AREA OF THE MACAQUE - ANATOMIC LOCATION AND VISUAL RESPONSE PROPERTIES
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DOI：
10.1152/jn.1993.69.3.902
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发表时间：
1993-03-01
影响因子：
2.5
通讯作者：
GOLDBERG, ME
中科院分区：
文献类型：
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作者：
COLBY, CL;DUHAMEL, JR;GOLDBERG, ME
1.猕猴的中颞区(MT)投射到顶内沟。我们在这里描述了在顶内沟深处的一个离散的区域，含有神经元，其反应特性类似于报道的MT区域。我们称这一区域为生理上定义的顶腹区，或VIP。在本研究中，我们记录了警觉猕猴VIP中的单个神经元，并研究了它们的视觉和眼动反应特性。区域VIP对移动刺激的方向具有高度的选择性。在我们的样本中，72/88(80%)的神经元对沿首选方向移动的刺激的反应至少是在零方向移动的刺激的两倍。对顺向移动的刺激的平均反应是对相反方向的刺激反应的9.5倍，而在MT3区神经元的平均反应是10.9倍。许多神经元对刺激运动的速度也有选择性。来自25个神经元的定量数据表明，偏爱速度的分布范围为10到320度/S。平均而言，速度调谐的程度是报道的MT区的两倍。有些神经元(22/41)对刺激呈现的距离有选择性，倾向于在脸部附近(20 cm以内)或非常近(5 cm以内)呈现相同视角和亮度的刺激。当单眼测试时，这些神经元保持了对近刺激的偏好，这表明除了视差之外的视觉线索可以支持这种反应。这些神经元通常不能被切线屏幕(57厘米处)上出现的小斑点驱动。一些VIP神经元对向动物移动的刺激反应最好。对于这些细胞来说，视觉运动的绝对方向并不像刺激的轨迹那么重要：最好的刺激是从任何方向朝面部某一特定点移动的刺激。VIP神经元不活跃，与眼球跳动有关。一些神经元(10/17)在平稳追逐小目标的过程中处于活跃状态。VIP区的方向和速度选择性占优势，提示它和背侧流中的其他视区一样，可能参与视觉运动的分析。
1. The middle temporal area (MT) projects to the intraparietal sulcus in the macaque monkey. We describe here a discrete area in the depths of the intraparietal sulcus containing neurons with response properties similar to those reported for area MT. We call this area the physiologically defined ventral intraparietal area, or VIP. In the present study we recorded from single neurons in VIP of alert monkeys and studied their visual and oculomotor response properties.2. Area VIP has a high degree of selectivity for the direction of a moving stimulus. In our sample 72/88 (80%) neurons responded at least twice as well to a stimulus moving in the preferred direction compared with a stimulus moving in the null direction. The average response to stimuli moving in the preferred direction was 9.5 times as strong as the response to stimuli moving in the opposite direction, as compared with 10.9 times as strong for neurons in area MT.3. Many neurons were also selective for speed of stimulus motion. Quantitative data from 25 neurons indicated that the distribution of preferred speeds ranged from 10 to 320-degrees/s. The degree of speed tuning was on average twice as broad as that reported for area MT.4. Some neurons (22/41) were selective for the distance at which a stimulus was presented, preferring a stimulus of equivalent visual angle and luminance presented near (within 20 cm) or very near (within 5 cm) the face. These neurons maintained their preference for near stimuli when tested monocularly, suggesting that visual cues other than disparity can support this response. These neurons typically could not be driven by small spots presented on the tangent screen (at 57 cm).5. Some VIP neurons responded best to a stimulus moving toward the animal. The absolute direction of visual motion was not as important for these cells as the trajectory of the stimulus: the best stimulus was one moving toward a particular point on the face from any direction.6. VIP neurons were not active in relation to saccadic eye movements. Some neurons (10/17) were active during smooth pursuit of a small target.7. The predominance of direction and speed selectivity in area VIP suggests that it, like other visual areas in the dorsal stream, may be involved in the analysis of visual motion.