Does Morphology Influence Temporal Plasticity?
Does Morphology Influence Temporal Plasticity?
复制标题
形态会影响时间可塑性吗？
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
A. V. Ooyen
中科院分区：
文献类型：
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作者：
D. Sterratt;A. V. Ooyen
将有界权重独立时间可塑性规则应用于来自独立泊松放电突触前神经元的突触到基于电导的整合和放电神经元上导致突触强度的双峰分布（Song等人，2000年）。我们扩展了这个模型，以研究在树突树上传播突触的影响。结果表明，远端突触往往失去了近端的竞争突触的强度。与预期相反，在增强和抑制之间具有更平滑过渡的可塑性规则的版本对分布几乎没有影响，或者导致所有突触丢失。
Applying bounded weight-independent temporal plasticity rule to synapses from independent Poisson firing presynaptic neurons onto a conductance-based integrate-and-fire neuron leads to a bimodal distribution of synaptic strength (Song et al., 2000). We extend this model to investigate the effects of spreading the synapses over the dendritic tree. The results suggest that distal synapses tend to lose out to proximal ones in the competition for synaptic strength. Against expectations, versions of the plasticity rule with a smoother transition between potentiation and depression make little difference to the distribution or lead to all synapses losing.