Parylene Photonic Microimager for Implantable Imaging

Parylene Photonic Microimager for Implantable Imaging
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用于植入成像的聚对二甲苯光子微成像仪

DOI:
10.1109/embc46164.2021.9630912
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发表时间:
2021
期刊:
43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC
影响因子:
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通讯作者:
Chamanzar, Maysamreza
Chamanzar, Maysamreza
中科院分区:
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文献类型:
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作者:
Reddy, Jay W.;Malekoshoaraie, Mohammad H.;Hassanzade, Vahid;Venkateswaran, Ramgopal;Chamanzar, Maysamreza

文献摘要

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我们最近推出了一个完全灵活,紧凑的光子平台,聚对二甲苯光子。在这里,我们展示了一个Parylene光子波导阵列微成像仪,在200 µm×1000 µm的区域内,沿x轴的光源定位精度为17.04 µ m沿着,沿y轴的光源定位精度为30.07 µm沿着。我们展示了使用显微成像仪阵列对小鼠脑组织进行荧光成像的可行性。临床相关性-植入式显微成像仪可用于临床术中监测以及研究中具有细胞类型特异性的结构和功能成像。
We have recently introduced a fully flexible, compact photonic platform, Parylene photonics. Here, we demonstrate a Parylene photonic waveguide array microimager with a light source localization accuracy of 17.04 µm along the x-axis and 30.07 µm along the y-axis over a 200 µm×1000 µm region. We show the feasibility of fluorescent imaging from mouse brain tissue using the microimager array.Clinical Relevance— Implantable microimagers can be used for clinical intraoperative monitoring as well as structural and functional imaging with cell-type specificity in research.