Fabrication of polymer brush surfaces with highly-ordered perfluoroalkyl side groups at the brush end and their antibiofouling properties.
Fabrication of polymer brush surfaces with highly-ordered perfluoroalkyl side groups at the brush end and their antibiofouling properties.
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DOI：
10.1039/c5tb00210a
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发表时间：
2015-05
期刊：
影响因子：
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通讯作者：
Lin Wang;Xiang Chen;Xinyu Cao;Jianquan Xu;B. Zuo;Li Zhang;Xinping Wang;Juping Yang;Yanqing Yao
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文献类型：
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作者：
Lin Wang;Xiang Chen;Xinyu Cao;Jianquan Xu;B. Zuo;Li Zhang;Xinping Wang;Juping Yang;Yanqing Yao
采用“接枝”法在Au基底上成功地制备了刷端含有2-全氟辛基乙基甲基丙烯酸酯单元的丙烯酸酯嵌段聚合物刷（Au-PMMA 65-b-PODMAy-ec-FMA 2）。XPS、接触角、椭偏仪和纳米力学测试结果表明，随着聚甲基丙烯酸十八酯聚合度（y）的增加，刷表面全氟烷基侧链的有序性和垂直取向性增强，当y = 24时，刷表面全氟烷基侧链形成结晶结构。蛋白质吸附的研究表明，纤维蛋白原的吸附质量下降的刷端的全氟烷基侧链的结构的顺序增加。当刷体表面的全氟烷基形成晶体结构时，刷体表面仅有微量纤维蛋白原吸附。本工作表明，蛋白质抵抗性能大大提高，通过构建聚合物刷表面与全氟烷基侧链的有序和垂直取向的结构。
Acrylate block polymer brushes (Au-PMMA65-b-PODMAy-ec-FMA2) with two 2-perfluorooctylethyl methacrylate units at the brush end were successfully prepared on an Au substrate using a "grafting to" method. Characterization by XPS, contact angle measurement, ellipsometry and nanomechanical measurement showed that a well-ordered and perpendicularly oriented structure of the perfluoroalkyl side chains on the brush surface was enhanced with an increasing degree of polymerization (y) of poly (n-octadecyl methacrylate), and a crystalline structure of perfluoroalkyl side chains formed when y was equal to 24. Protein adsorption studies indicated that the adsorbed mass of fibrinogen decreased with an increasing order of the structure of the perfluoroalkyl side chains at the brush end. When the perfluoroalkyl group on the brush surface formed a crystal structure, there was only trace fibrinogen adsorption on the brush surface. This work demonstrates that the protein-resistant performance was enhanced greatly by constructing polymer brush surfaces with well-ordered and perpendicularly oriented structures of the perfluoroalkyl side chains.