Comparative Role of Aedes albopictus and Aedes aegypti in the Emergence of Dengue and Chikungunya in Central Africa
Comparative Role of Aedes albopictus and Aedes aegypti in the Emergence of Dengue and Chikungunya in Central Africa
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DOI：
10.1089/vbz.2009.0005
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发表时间：
2010-04-01
影响因子：
2.1
通讯作者：
Simard, Frederic
中科院分区：
文献类型：
--
作者：
Paupy, Christophe;Ollomo, Benjamin;Simard, Frederic
自 1991 年在尼日利亚发现以来，白纹伊蚊已入侵中非大部分地区，该地区是伊蚊的栖息地。埃及伊蚊也会出现。评估Ae入侵之间的关系。为了应对白纹伊蚊和最近出现的登革热病毒（DENV）和基孔肯雅病毒（CHIKV），我们对喀麦隆收集的人群进行了媒介能力实验，并在加蓬登革热病毒和基孔肯雅病毒同时流行期间进行了现场调查。总体而言，Ae 之间的感染率和传播率没有显着差异。白纹伊蚊和伊蚊。当暴露于滴度分别为 10(8.1) 蚊子感染剂量 50/mL 和 10(7.5) 噬菌斑形成单位/mL 的 DENV 2 型和 CHIKV 时，埃及伊蚊。现场调查表明，Ae.白纹伊蚊很容易咬人，数量众多，而且数量超过伊蚊。埃及伊蚊在很大程度上集中在加蓬，特别是在郊区环境中。尽管如此，Ae.埃及伊蚊在利伯维尔城市化程度较高的中部地区占主导地位。在该市，CHIKV 和 DENV 仅在伊蚊中检测到。白纹伊蚊。这些数据强烈表明 Ae。 2007年，白纹伊蚊是利伯维尔这两种病毒的主要传播媒介，影响了该地区DENV和CHIKV的流行病学。
Since its discovery in Nigeria in 1991, Aedes albopictus has invaded much of Central Africa, a region where Ae. aegypti also occurs. To assess the relationship between the invasion by Ae. albopictus and the recent emergence of dengue virus (DENV) and chikungunya virus (CHIKV), we undertook vector competence experiments on populations collected from Cameroon and conducted field investigations during concurrent epidemics of DENV and CHIKV in Gabon. Overall, infection and dissemination rates were not significantly different between Ae. albopictus and Ae. aegypti when exposed to titers of 10(8.1) mosquito infectious dose 50/mL and 10(7.5) plaque forming units/mL of DENV type 2 and CHIKV, respectively. Field investigations showed that Ae. albopictus readily bit man, was abundant, and outnumbered Ae. aegypti to a large extent in Gabon, particularly in suburban environments. Nevertheless, Ae. aegypti was predominant in the more urbanized central parts of Libreville. In this city, CHIKV and DENV were detected only in Ae. albopictus. These data strongly suggest that Ae. albopictus acted as the major vector of both viruses in Libreville in 2007, impacting on the epidemiology of DENV and CHIKV in this area.