Regulation of lipoprotein lipase secretion by mouse peritoneal macrophages.
Regulation of lipoprotein lipase secretion by mouse peritoneal macrophages.
复制标题
小鼠腹腔巨噬细胞脂蛋白脂肪酶分泌的调节。
DOI:
10.1016/0006-291x(87)90443-8
复制
发表时间:
1987
影响因子:
3.1
通讯作者:
Khoo,JC
中科院分区:
文献类型:
--
作者:
Goldberg,DI;Khoo,JC
Resident mouse peritoneal macrophages in culture spontaneously secrete lipoprotein lipase. Secretion of lipoprotein lipase was 10-fold greater in thioglycollate-elicited and 6-fold greater in mineral oil-elicited macrophages. The increase in enzyme secretion was dependent on protein synthesis and glycosylation of the newly synthesized enzyme. The addition of 1 to 500 ng per ml of lipopolysaccharide to the culture medium resulted in a dose-dependent inhibition of lipoprotein lipase secretion. Thus, secretion of macrophage lipoprotein lipase is a regulated process, and may be increased as part of the response to inflammation. This may have important implications in the atherogenic process in the arterial wall.
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DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Khoo,JC;Mahoney,EM;Steinberg,D
通讯作者:
Steinberg,D
DOI:
--
发表时间:
1983
期刊:
影响因子:
--
作者:
R. Jackson
通讯作者:
R. Jackson
DOI:
--
发表时间:
1982
期刊:
Biochemical and Biophysical Research Communications - BBRC
影响因子:
--
作者:
P. Wang;A. Ungar;J. Bliumis;P. Bukberg;J. Gibson;W. Brown
通讯作者:
W. Brown
DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Khoo,JC;Mahoney,EM;Witztum,JL
通讯作者:
Witztum,JL
DOI:
--
发表时间:
1983
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Lindqvist,P;Ostlund-Lindqvist,AM;Witztum,JL;Steinberg,D;Little,JA
通讯作者:
Little,JA