Association of contact to small children with a mild course of COVID-19.
Association of contact to small children with a mild course of COVID-19.
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DOI：
10.1016/j.ijid.2020.09.003
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发表时间：
2020-11
期刊：
影响因子：
--
通讯作者：
Schmidt HH
中科院分区：
文献类型：
--
作者：
Dugas M;Schrempf IM;Ochs K;Frömmel C;Greulich L;Neuhaus P;Tepasse PR;Schmidt HH
众所周知，幼儿中的严重 COVID-19 病例很少见。如果与儿童相关的感染可以预防严重的 COVID-19 病程，那么预计与幼儿密切和经常接触的成年人也可能更频繁地患上轻度的 COVID-19 病程。为了检验这一假设，德国对 4010 名康复的 COVID-19 患者进行了一项调查。共收集到 1186 个完整答案。其中6.9%的患者表示经常和10岁以下的儿童因工作相关接触，23.2%的患者有自己的小孩，这一比例高于预期。在接受重症监护治疗的相对较小的亚组中（n = 19），未与幼儿接触的患者所占比例过高。这些发现不能用这些患者的年龄、性别或体重指数分布来很好地解释，应该在其他环境中进行验证。
It is known that severe COVID-19 cases in small children are rare. If a childhood-related infection were protective against a severe course of COVID-19, it would be expected that adults with intensive and regular contact with small children also may have a mild course of COVID-19 more frequently. To test this hypothesis, a survey among 4010 recovered COVID-19 patients was conducted in Germany. 1186 complete answers were collected. 6.9% of these patients reported frequent and regular job-related contact with children below ten years of age, and 23.2% had their own small children, which was higher than expected. In the relatively small subgroup with intensive care treatment (n = 19), patients without contact with small children were overrepresented. These findings are not well explained by age, gender, or BMI distribution of those patients and should be validated in other settings.
影响因子：
64.5
作者：
Grifoni, Alba;Weiskopf, Daniela;Sette, Alessandro
通讯作者：
Sette, Alessandro