Hydrolysis of oligonucleotides by homogeneous Ce(IV)/EDTA complex
Hydrolysis of oligonucleotides by homogeneous Ce(IV)/EDTA complex
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DOI：
10.1246/cl.2000.356
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发表时间：
2000-04-05
影响因子：
1.6
通讯作者：
Komiyama, M
中科院分区：
文献类型：
--
作者：
Igawa, T;Sumaoka, J;Komiyama, M
EDTA的均相Ce（IV）配合物在生理条件下能迅速水解寡核苷酸。相反，二核苷酸不能水解到可测量的程度。DNA底物的聚合程度是催化反应的关键。
Homogeneous Ce(IV) complex of EDTA promptly hydrolyzes oligonucleotides under physiological conditions. In contrast, dinucleotides are not hydrolyzed to measurable extents. The degree of polymerization of DNA substrate is crucial for the present catalysis.