Adenomyosis and junctional zone changes in patients with endometriosis

Adenomyosis and junctional zone changes in patients with endometriosis
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DOI:
10.1016/j.ejogrb.2011.03.003
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发表时间:
2011-08-01
影响因子:
2.6
通讯作者:
Dueholm, M.
Dueholm, M.
中科院分区:
医学4区
文献类型:
--
作者:
Larsen, S. B.;Lundorf, E.;Dueholm, M.

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目的:探讨子宫内膜异位症结合区(JZ)的影像学表现,并与子宫腺肌病的影像学表现进行比较。为了尝试一个相关性的程度的腺肌浸润的浸润程度和阶段的子宫内膜异位症,研究设计:磁共振成像(MRI)的子宫进行了153名妇女怀疑深度浸润性子宫内膜异位症和计划的手术,并在一个参考组的129名妇女没有子宫内膜异位症,子宫切除术期间验证。详细描述了JZ和盆腔子宫内膜异位症的变化。子宫腺肌病的MRI诊断基于子宫切除术对照组的最佳标准。子宫内膜异位症的症状结果:子宫内膜异位症组中34.6%的妇女患有子宫腺肌症,而对照组为19.4(p 0.05)但深部浸润性直肠阴道子宫内膜异位症的存在和浸润的大小与子宫腺肌病或子宫腺肌病浸润的深度无关。在一组患有严重症状性子宫内膜异位症并计划手术的年轻女性中,对JZ的系统评价显示,三分之一患有子宫腺肌病,但子宫内膜细胞在子宫和腹膜中的浸润潜力仅在有限程度上对应。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
Objectives: To evaluate image findings in the junctional zone (JZ) in patients with endometriosis and correlate with image findings of adenomyosis. To attempt a correlation of the degree of adenomyotic infiltration with the degree of infiltration and stage of endometriosis.Study design: Magnetic resonance imaging (MRI) of the uterus was performed in 153 women with suspected deeply infiltrating endometriosis and planned surgery, and in a reference group of 129 women without endometriosis, verified during hysterectomy. Changes in the JZ and endometriosis in the pelvis were described in detail. Diagnosis of adenomyosis at MRI was based on optimal criteria derived from the hysterectomy control group. The stage of endometriosis (AFS stage) was determined during surgery.Results: In the group of women with endometriosis 34.6% had adenomyosis compared with 19.4% in the reference group (p 0.05) but the presence of deep infiltrative rectovaginal endometriosis and the size of infiltration were not correlated to adenomyosis or depth of infiltration of adenomyosis.Conclusions: In a group of young women with severe symptomatic endometriosis and planned surgery a systematic evaluation of the JZ revealed that one third had uterine adenomyosis, but the invasive potential of endometrial cells in the uterus and in the peritoneum corresponded only to a limited degree. (C) 2011 Elsevier Ireland Ltd. All rights reserved.