A Conjunctiva OxygenSensor forTranscutaneous Monitoring
A Conjunctiva OxygenSensor forTranscutaneous Monitoring
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用于经皮监测的结膜氧传感器
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
T. Sawada
中科院分区：
文献类型：
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作者：
T. Sawada
研制了一种用于经皮结膜氧合监测的轻薄灵活的氧传感器。利用光刻和溅射技术制备了宽度为3 mm、厚度为84 pm的耐磨氧传感器。该传感器用于-400 mV与Ag/AgCl的恒定电压的电化学测量。该传感器可测量溶解氧，校准范围为0~7.31 mg/L，在沥青中也能提供60%的氧气，在90%的恒定电流下的响应时间约为45秒。然后将可穿戴式氧合器应用于经皮结膜氧合监测。这个可穿戴的氧气传感器安装在一只日本白兔的结膜上。兔吸入大气空气和60%氧气，监测传感器的输出电流。在升温过程中，传感器输出与吸入氧气浓度的变化同步增减。这表明该传感器可以在不升温的情况下成为新的经皮氧传感器。
A flexible andthinoxygensensor wasdeveloped for transcutaneous oxygenmonitoring at conjunctiva. The wearable oxygensensor (width: 3mm,thickness: 84pm)was fabricated bypouching KCIelectrolyte solution between non- permeable membraneandgas-permeable membranewithPt- andAg/AgCl- electrodes patterned using photolithography and sputtering. Thiswearableoxygensensorwas applied to electrochemical measurement witha constant voltage of- 400mVversus Ag/AgCl. Thissensor wasabletomeasurethe dissolved oxygenwithacalibration rangefrom0to7.31mg/l. Thesensor wasalsoevaluated ingasphasebyproviding 60% oxygenandresponse timetoreach90% ofthesteady current afterproviding was approximately 45 seconds. Thenthe wearable oxygensensorwasapplied tothetranscutaneous oxygenmonitoring atconjunctiva. Thewearable oxygensensor wasattached toconjunctiva ofaJapanese whiterabbit. The rabbit inhaled atmospheric airand60% oxygen, theoutput current ofthesensorwasmonitored. Withoutwarming, the sensor output increased anddecreased synchronously withthe changeofoxygenconcentration thattherabbit inhaled. This suggests thatthesensor canbeanewtranscutaneous oxygen sensor without warming.
氧气在人角膜体内的扩散。
影响因子：
4.4
作者：
Weissman,BA;Fatt,I;Rasson,J
通讯作者：
Rasson,J