Frequent occurrence of the tetrodotoxin-bearing horseshoe crab Carcinoscorpius rotundicauda in Vietnam
Frequent occurrence of the tetrodotoxin-bearing horseshoe crab Carcinoscorpius rotundicauda in Vietnam
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DOI：
10.1007/s12562-008-0041-5
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发表时间：
2009-04-01
影响因子：
1.9
通讯作者：
Kodama, Masaaki
中科院分区：
文献类型：
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作者：
Dao, Ha Viet;Takata, Yoshinobu;Kodama, Masaaki
采用高效液相色谱法和LC-MS/MS联用法对采自越南翁头省滩海村的圆尾鳞蟹标本中河豚毒素(TTX)进行检测。在分析的12个样本中，有10个样本的软组织显示出相当大的TTX水平，使其对人类消费不安全(81.2+/-A 50.3MU/g)。麻风性贝毒(PSP)毒素也在所有标本中检测到，但水平较低。这些发现表明，TTX含量高的圆尾鱼标本的出现频率明显较高，TTX是该地区食用圆尾鱼造成食物中毒的原因之一。
Tetrodotoxin (TTX) was detected by HPLC and LC-MS/MS in specimens of the horseshoe crab Carcinoscorpius rotundicauda collected from Tan Hai village, Vung Tau province, Vietnam, where cases of poisoning due to the consumption of horseshoe crab have frequently been reported. The soft tissue from 10 out of the 12 specimens analyzed showed considerable levels of TTX, making them unsafe for human consumption (81.2 +/- A 50.3 MU/g). Paralytic shellfish poisoning (PSP) toxins were also detected in all of the specimens, but the levels were low. These findings show that the frequency of occurrence of C. rotundicauda specimens with a high level of TTX is significantly high, and that the TTX is responsible for the food poisonings caused by the consumption of C. rotundicauda in this area.