A systematic review and meta-analysis of randomized controlled trials of the impact of sleep duration on adiposity and components of energy balance.
A systematic review and meta-analysis of randomized controlled trials of the impact of sleep duration on adiposity and components of energy balance.
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DOI：
10.1111/obr.12296
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发表时间：
2015-09
期刊：
影响因子：
--
通讯作者：
Allison DB
中科院分区：
文献类型：
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作者：
Capers PL;Fobian AD;Kaiser KA;Borah R;Allison DB
最近人类的流行病学和生态学趋势表明，睡眠时间和能量平衡之间可能存在因果关系。我们的目标是找到实验证据，测试睡眠时间与身体成分、食物摄入量或与食物摄入量相关的生物标记物之间的关系。截至2014年8月7日，我们使用六个数据库进行了系统的文献综述。我们寻求随机对照试验的报告，其中睡眠时间被操纵，测量的结果是体重或其他身体成分指标、食物摄入量和/或与进食有关的生物标志物。我们发现了18项符合所有标准的独特研究：8项与体重有关的研究(4项睡眠增加，4项睡眠减少)；4项关于食物摄入量的研究；4项关于睡眠限制总能量消耗的研究；3项关于呼吸商的研究；4项关于瘦素和/或Ghrelin的研究。很少有对照实验研究涉及睡眠对体重/成分和饮食的影响的问题。现有的实验文献表明，睡眠限制增加了食物摄入量和总能量消耗，但通过体重变化对综合能量平衡的影响不一致。未来有必要进行对照试验，研究睡眠增加对体重/能量平衡因素的影响。
Recent epidemiological and ecological trends in humans indicate a possible causal relationship between sleep duration and energy balance. We aimed to find experimental evidence that has tested this relationship between sleep duration and measures of body composition, food intake or biomarkers related to food intake. We conducted a systematic literature review using six databases through August 7, 2014. We sought reports of randomized controlled trials where sleep duration was manipulated and measured outcomes were body weight or other body composition metrics, food intake, and/or biomarkers related to eating. We found 18 unique studies meeting all criteria: eight studies with an outcome of body weight (4 - increased sleep, 4 - reduced sleep); four studies on food intake; four studies of sleep restriction on total energy expenditure and three of respiratory quotient; four studies on leptin and/or ghrelin. Few controlled experimental studies have addressed the question of the effect of sleep on body weight/composition and eating. The available experimental literature suggests that sleep restriction increases food intake and total energy expenditure with inconsistent effects on integrated energy balance as operationalized by weight change. Future controlled trials that examine the impact of increased sleep on body weight/energy balance factors are warranted.