Insulinoma in the elderly : a report of three cases and review literature
Insulinoma in the elderly : a report of three cases and review literature
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老年人胰岛素瘤三例报告及文献复习
DOI：
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
L. Gaal
中科院分区：
文献类型：
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作者：
K. Bernaerts;Lynn Gers;A. Verhaegen;C. Block;L. Gaal
胰岛素瘤是罕见的胰腺胰岛细胞肿瘤，以胰岛素分泌过多导致的空腹低血糖为主要临床表现。选择的治疗方法是手术。对于老年人来说，诊断和治疗可能具有挑战性。该人群围手术期风险升高往往导致放弃手术选择。营养方法和药物治疗通常是首选。然而，它们并不总是足以控制低血糖症状。对于这些患者，可以考虑其他治疗方案，例如射频消融和栓塞，尽管有关在该特定适应症和人群中使用这些策略的数据有限。我们报告了三例老年胰岛素瘤病例，并探索了不同的治疗方案。
Insulinoma are rare pancreatic islet cell tumors with fasting hypoglycemia due to excessive insulin secretion as the main clinical expression. The treatment of choice is surgery. In the elderly, diagnosis and treatment can be challenging. The elevated perioperative risks in this population often lead to forsake the option of surgery. Nutritional approaches and medical treatment are then often preferred. However they are not always sufficient in controlling the symptoms of hypoglycemia. In these patients other treatment options such as radiofrequency ablation and embolization are considered, although only limited data are available on the use of these strategies in this specific indication and population. We report three cases of insulinoma in elderly patients for which different treatment options were explored.