Co-occurring depression and obsessive-compulsive disorder: A dimensional network approach.

Co-occurring depression and obsessive-compulsive disorder: A dimensional network approach.
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共存的抑郁症和强迫症:维度网络方法。

DOI:
10.1016/j.jad.2022.08.101
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发表时间:
2022
影响因子:
6.6
通讯作者:
Riemann,BradleyC
Riemann,BradleyC
中科院分区:
医学2区
文献类型:
--
作者:
Hellberg,SamanthaN;Abramowitz,JonathanS;Ojalehto,HeidiJ;Butcher,MeganW;Buchholz,JenniferL;Riemann,BradleyC

文献摘要

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背景抑郁和强迫症(OCD)症状经常同时发生,并且已经探索了这种同时发生的一些可能的解释,包括共同的生物学和心理社会危险因素。网络方法为抑郁症和强迫症之间的联系提供了一个新的假设:这些症状的功能相互关系。在这一领域的少数网络研究主要依赖于项目,而不是过程级的结构,并没有检查dimensioned.MethodsNetwork分析方法的关系,从463寻求治疗的成人强迫症的数据。患者完成强迫症和抑郁症的自我报告措施。因子分析用于推导过程(即,节点)以包括在网络中。网络进行计算,和中心性,桥梁,和稳定性statisticsexamined.ResultsNetworks之间表现出积极的关系,具体的强迫症和抑郁症状。强迫症(特别是令人反感的想法)、消极情感和认知-躯体变化(例如,集中注意力的困难)是网络的核心。在对称性强迫症症状和认知-躯体改变之间观察到独特的关系。伤害相关的强迫症症状和抑郁症之间没有直接的联系observed.ConclusionsOur结果汇集了以前的研究结果,这表明,无论是消极的情感和心理的变化是重要的,考虑在检查强迫症和抑郁症之间的关系。增加对强迫症症状内容的异质性的考虑是改善临床概念化的关键,特别是当考虑强迫症与其他疾病同时发生时。
BackgroundDepressive and obsessive-compulsive (OCD) symptoms often co-occur and a number of possible explanations for this co-occurrence have been explored, including shared biological and psychosocial risk factors. Network approaches have offered a novel hypothesis for the link between depression and OCD: functional inter-relationships across the symptoms of these conditions. The few network studies in this area have relied largely on item, rather than process-level constructs, and have not examined relationships dimensionally.MethodsNetwork analytic methods were applied to data from 463 treatment-seeking adults with OCD. Patients completed self-report measures of OCD and depression. Factor analysis was used to derive processes (i.e., nodes) to include in the network. Networks were computed, and centrality, bridge, and stability statistics examined.ResultsNetworks showed positive relations among specific OCD and depressive symptoms. Obsessions (particularly repugnant thoughts), negative affectivity, and cognitive-somatic changes (e.g., difficulty concentrating) were central to the network. Unique relations were observed between symmetry OCD symptoms and cognitive-somatic changes. No direct link between harm-related OCD symptoms and depression was observed.ConclusionsOur results bring together prior findings, suggesting that both negative affective and psychomotor changes are important to consider in examining the relationship between OCD and depression. Increased consideration of heterogeneity in the content of OCD symptoms is key to improving clinical conceptualizations, particularly when considering the co-occurrence of OCD with other disorders.