Manganese-catalyzed oxidative homo-coupling of aryl Grignard chlorides
Manganese-catalyzed oxidative homo-coupling of aryl Grignard chlorides
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DOI：
10.1016/j.jorganchem.2008.12.021
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发表时间：
2009-03-01
影响因子：
2.3
通讯作者：
Xue, Weizhe
中科院分区：
文献类型：
--
作者：
Zhou, Zhiming;Xue, Weizhe
以氯化锰为催化剂，成功地实现了芳基氯化镁的锰催化均偶联制联苯。在化学计量量的1,2-二氯乙烷存在下，以10 mol%的MnCl2为催化剂，多种芳基氯化镁有效地转化为相应的对称双芳基。由于制备格氏试剂的芳酰氯比相应的溴化物和碘化物更便宜，更容易获得，因此该方法应成为制备对称双芳基的首选方法。(C) 2008 Elsevier B.V.版权所有
Manganese-catalyzed homo-coupling of aryl magnesium chlorides to give biphenyls was successfully achieved using manganese chloride as catalyst. A variety of aryl magnesium chlorides were efficiently converted into the corresponding symmetrical biaryls using 10 mol% MnCl2 as catalyst in the presence of a stoichiometric amount of 1,2-dichloroethane. Since the aryl chlorides, from which the Grignard reagents were prepared, are cheaper and more readily available that the corresponding bromides and iodides this procedure should become the method of choice for preparing symmetrical biaryls. (C) 2008 Elsevier B.V. All rights reserved.