Intrinsic and extrinsic carbohydrates in the vagina: A short review on vaginal glycogen.
Intrinsic and extrinsic carbohydrates in the vagina: A short review on vaginal glycogen.
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DOI：
10.1016/j.ijbiomac.2018.01.166
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发表时间：
2018-06
影响因子：
8.2
通讯作者：
R. Tester;F. Al-Ghazzewi
中科院分区：
文献类型：
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作者：
R. Tester;F. Al-Ghazzewi
人类阴道中乳酸菌（i）存在糖原的原因和（ii）利用糖原的机制尚未完全了解。很可能阴道上皮细胞同时产生糖原和α-淀粉酶，其中酶在阴道内解聚多糖。只有这些解聚的残留物然后被乳酸菌用于生长。乳酸菌不能直接代谢糖原，因为它们不能产生α-淀粉酶。然而，这些细菌可以选择性地代谢外源性碳水化合物（如益生元）以有效地生长。这些碳水化合物的利用问题在阴道内被认为是在这个简短的审查。
The reasons for (i) the presence and (ii) mechanisms of utilisation of glycogen by the lactic acid bacteria in the human vaginal tract are not well understood. It is probable that the vaginal epithelia produce both glycogen and α-amylase where the enzyme depolymerises the polysaccharide within the vagina itself. Only these depolymerised residues are then utilised for growth by the lactic acid bacteria. The lactic acid bacteria cannot metabolise the glycogen directly due to their incapacity to produce the α-amylase enzyme. These bacteria may, however, metabolise exogenous carbohydrates (such as prebiotics) selectively for growth effectively. These carbohydrate utilisation issues within the vagina are considered in this short review.