Apollo: a sequence annotation editor.
Apollo: a sequence annotation editor.
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DOI：
10.1186/gb-2002-3-12-research0082
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发表时间：
2002
期刊：
影响因子：
12.3
通讯作者：
Clamp ME
中科院分区：
文献类型：
--
作者：
Lewis SE;Searle SM;Harris N;Gibson M;Lyer V;Richter J;Wiel C;Bayraktaroglu L;Birney E;Crosby MA;Kaminker JS;Matthews BB;Prochnik SE;Smithy CD;Tupy JL;Rubin GM;Misra S;Mungall CJ;Clamp ME
Apollo 的开发是为了使管理者能够仔细检查基因组注释并对其进行编辑。 FlyBase 生物学家成功使用 Apollo 注释了果蝇基因组。用于注释基因组序列的纯计算方法存在公认的不准确性，因此需要一种交互式工具，以便生物学专家通过查看和独立评估支持每个注释的数据来完善这些近似值。 Apollo 的开发就是为了满足这一需求，使管理者能够仔细检查基因组注释并对其进行编辑。 FlyBase 生物学家成功地使用 Apollo 注释了果蝇基因组，并且它越来越多地被用作开发其他基因组项目的定制注释编辑工具的起点。
Apollo was developed to enable curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome. The well-established inaccuracy of purely computational methods for annotating genome sequences necessitates an interactive tool to allow biological experts to refine these approximations by viewing and independently evaluating the data supporting each annotation. Apollo was developed to meet this need, enabling curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome and it is increasingly being used as a starting point for the development of customized annotation editing tools for other genome projects.