Detection thresholds for an olfactory mixture and its three constituent compounds
Detection thresholds for an olfactory mixture and its three constituent compounds
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嗅觉混合物及其三种成分的检测阈值
DOI：
10.1093/chemse/18.6.723
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发表时间：
1993
期刊：
影响因子：
3.5
通讯作者：
J. Cometto
中科院分区：
文献类型：
--
作者：
Matthew Q. Patterson;J. C. Stevens;W. Cain;J. Cometto
作者：帕特森，马修·Q；史蒂文斯，约瑟夫·C；凯恩，威廉·S；恩里克·穆尼兹彗星 |摘要：根据一些报告，单一亚阈值气味剂可以同时被感知。即，它们可以表现出混合物加和性。本研究测量了 1-丁醇、2-戊酮和乙酸正丁酯混合物的阈值，并分别测量了其中每一种的阈值。结果是“完全”相加，混合物中每种化合物的阈值浓度（通过气相色谱法测量）分别是每种成分的三分之一。早期的阈值研究也声称完全可加性甚至超可加性（协同作用）；在这方面，它们与本研究一样，与更多的阈值上混合物研究不同，后者产生不完美的可加性（低可加性）。混合物不仅可以提高灵敏度，还可以提高稳定性；混合物的受试者间变异性小于成分的受试者间变异性。受试者为 20 名年轻人（18-26 岁）和 20 名老年人（69-91 岁），他们在 2 天内给出了两组阈值。与早期的研究结果一致，老年人的阈值平均比年轻人高（约20倍），但完全可加性仍然存在，即使他们在浓度连续体的不同部分进行操作。该研究通过比较在同一天和不同天检查的相同和不同化合物之间的相关性来观察阈值的测试间可靠性。
Author(s): Patterson, Matthew Q; Stevens, Joseph C; Cain, William S; Cometto-Muniz, J. Enrique | Abstract: Single sub-threshold odorants can, according to a few reports, become perceptible in concert. That is, they can exhibit mixture additivity. The present study measured thresholds for mixture of 1-butanol, 2-pentanone, and n-butyl acetate, and for each of these separately. 'Complete' additivity resulted, in that the threshold concentration of each compound in the mixture (measured by gas chromatography) turned out to be one-third of each component separately. Earlier threshold studies also claimed complete additivity and even hyper-additivity (synergism); in this regard they, like this study, differ from the more numerous studies of suprathreshold mixtures, which yield imperfect additivity (hypo-additivity). Mixtures not only enhance sensitivity, but they may also promote stability; intersubject variability was smaller for the mixture than for the components. Subjects were 20 young (18–26 years) and 20 elderly (69–91 years) persons, who gave two sets of thresholds on 2 days. Concordant with earlier findings, the elderly's thresholds averaged higher (≈ 20 times) than the young's, but complete additivity nevertheless held, even though they operated over different portions of the concentration continuum. The study affords a look at inter-test reliability of thresholds by comparing correlations between same and different compounds examined on same and different days.
通过阈值、幅度匹配和气味识别来衡量老年嗅觉缺陷。
影响因子：
3.7
作者：
Stevens,JC;Cain,WS
通讯作者：
Cain,WS
嗅觉敏感性：可靠性、普遍性以及与衰老的关联。
DOI：
10.1037//0096-1523.17.2.382
发表时间：
1991
期刊：
Journal of experimental psychology. Human perception and performance
影响因子：
--
作者：
Cain,WS;Gent,JF
通讯作者：
Gent,JF