Fungicidal Action of Hydroxyl Radicals Generated by Ultrasound in Water
Fungicidal Action of Hydroxyl Radicals Generated by Ultrasound in Water
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DOI：
10.3164/jcbn.08-261
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发表时间：
2009-09-01
影响因子：
2.4
通讯作者：
Niwano, Yoshimi
中科院分区：
文献类型：
--
作者：
Iwasawa, Atsuo;Saito, Keita;Niwano, Yoshimi
众所周知，水中的羟基自由基是通过超声产生的。这项研究与电子自旋共振自旋捕获技术表明，羟基自由基的产生与超声时间和水温呈正相关。对毛癣菌属有明显的杀菌作用。通过研究培养的细胞以及通过透射和扫描电子显微镜观察到的细胞质和表面结构的降解，表明热水中的超声波对于皮肤真菌污染的灭菌是有效的，并且可以有效地治疗真菌感染。
It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.