Diversity among Tacaribe serocomplex viruses (family Arenaviridae) naturally associated with the Mexican woodrat (Neotoma mexicana)

Diversity among Tacaribe serocomplex viruses (family Arenaviridae) naturally associated with the Mexican woodrat (Neotoma mexicana)
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DOI:
10.1016/j.virusres.2008.01.005
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发表时间:
2008-05-01
期刊:
影响因子:
5
通讯作者:
Fulhorst, Charles F.
Fulhorst, Charles F.
中科院分区:
医学3区
文献类型:
--
作者:
Cajimat, Maria N. B.;Milazzo, Mary Louise;Fulhorst, Charles F.

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糖蛋白前体和核衣壳蛋白基因序列的分析结果表明,从亚利桑那州捕获的墨西哥林木(Neotoma Miciana)上分离到的ArenaVirus是一个新种的毒株(拟命名为Skinner Tank Virus),从科罗拉多州、新墨西哥州和犹他州捕获的墨西哥林木上分离的ArenaVirus是白水Arroyo病毒的毒株或与白水Arroyo病毒亲缘关系密切的物种。对糖蛋白前体序列和核衣壳蛋白序列的两两比较显示,从科罗拉多州、新墨西哥州和犹他州捕获的墨西哥林木中分离的病毒与白水阿罗约病毒原型株AV 9310135之间存在高度差异,该病毒最初是从新墨西哥州捕获的白喉木树(Neotoma Albigula)中分离出来的。从概念上讲,来自科罗拉多州、新墨西哥州和犹他州的病毒和病毒株AV 9310135可以归入Arenaviridae科的ArenaVirus属的一个物种复合体中。(C)2008爱思唯尔B.V.保留所有权利。
The results of analyses of glycoprotein precursor and nucleocapsid protein gene sequences indicated that an arenavirus isolated from a Mexican woodrat (Neotoma mexicana) captured in Arizona is a strain of a novel species (proposed name Skinner Tank virus) and that arenaviruses isolated from Mexican woodrats captured in Colorado, New Mexico, and Utah are strains of Whitewater Arroyo virus or species phylogenetically closely related to Whitewater Arroyo virus. Pairwise comparisons of glycoprotein precursor sequences and nucleocapsid protein sequences revealed a high level of divergence among the viruses isolated from the Mexican woodrats captured in Colorado, New Mexico, and Utah and the Whitewater Arroyo virus prototype strain AV 9310135, which originally was isolated from a white-throated woodrat (Neotoma albigula) captured in New Mexico. Conceptually, the viruses from Colorado, New Mexico, and Utah and strain AV 9310135 could be grouped together in a species complex in the family Arenaviridae, genus Arenavirus. (c) 2008 Elsevier B.V. All rights reserved.