[Formula: see text]FarmApp: a new assessment of cognitive control and memory for children and young people with neurodevelopmental difficulties.
[Formula: see text]FarmApp: a new assessment of cognitive control and memory for children and young people with neurodevelopmental difficulties.
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[公式：见文字]FarmApp：针对有神经发育困难的儿童和青少年的认知控制和记忆力的新评估。
DOI：
10.1080/09297049.2022.2054968
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Brkic D
中科院分区：
文献类型：
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作者：
Brkic D
我们介绍了一种新的基于触摸屏的方法，测量有神经发育困难的儿童和年轻人的认知控制和记忆方面，包括智力残疾(ID)。FarmApp是一个游戏化的、基于平板电脑的评估工具，测量进行/不进行反应的速度、反应抑制、视觉空间短期记忆广度和长期记忆。在这里，我们评估了该方法的可行性、有效性和实用性，包括测量两周内性能变化的好处。我们观察到：1)完成FarmApp测试的参与者比例高于传统的心理测量测试；2)当参与者有机会在家中进行两周的自定进度测试时，这一比例会增加；3)与ADHD相关的行为困难与所有尝试的平均进行/不进行有关，以及随着时间的推移进行/不进行的表现的变化，表明该方法对认知差异的敏感性与现实世界的相关性。我们还讨论了FarmApp在探索ID病因学和认知过程之间的联系方面的潜在效用。我们观察到两组ID参与者在GO/NO-GO任务中的差异，这两组参与者根据相关遗传变量(染色质相关和突触相关)的生理功能进行分层。此外，随着时间的推移，突触组在GO/NO-GO表现出更高程度的改善。这一结果潜在地为这一群体中导致认知困难的动态机制提供了信息。总而言之，FarmApp是一个可行、有效和有用的工具，为具有不同严重程度的神经发育困难的个人增加了获得认知评估的机会，并增加了监测表现随时间的变化和确定获得任务能力的能力的机会。
We introduce a new touchscreen-based method measuring aspects of cognitive control and memory, in children and young people with neurodevelopmental difficulties, including intellectual disability (ID). FarmApp is a gamified, tablet-based assessment tool measuring go/no-go response speed, response inhibition, visuospatial short-term memory span, and long-term memory. Here, we assessed the feasibility, validity, and utility of the method, including the benefits of measuring change in performance over two weeks. We observed that: 1) a higher proportion of participants completed FarmApp than traditional psychometric tests; 2) this proportion increased when participants had opportunity for two weeks of self-paced testing at home; 3) ADHD-relevant behavioral difficulties were associated with average go/no-go performance across all attempts, and change in go/no-go performance over time, indicating sensitivity of the method to cognitive differences with real-world relevance. We also addressed the potential utility of the FarmApp for exploring links between ID etiology and cognitive processes. We observed differences in go/no-go task between two groups of ID participants stratified by the physiological functions of associated genetic variants (chromatin-related and synaptic-related). Moreover, the synaptic group demonstrated higher degree of improvement in go/no-go performance over time. This outcome is potentially informative of dynamic mechanisms contributing to cognitive difficulties within this group. In sum, FarmApp is a feasible, valid, and useful tool increasing access to cognitive assessment for individuals with neurodevelopmental difficulties of variable severity, with an added opportunity to monitor variation in performance over time and determine capacity to acquire task competence.