Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract: Lethal Midline Granuloma— Wegener's Granulomatosis
Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract: Lethal Midline Granuloma— Wegener's Granulomatosis
复制标题
呼吸道致命肉芽肿病的耳科表现：致死性中线肉芽肿 — 韦格纳肉芽肿病
DOI：
10.1001/archotol.1961.00740020653003
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发表时间：
1961
影响因子：
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通讯作者：
Merle Lawrence
中科院分区：
文献类型：
--
作者：
I. Blatt;Merle Lawrence
本文的目的是描述致死性呼吸道肉芽肿的耳科特征。特别强调病理解剖学的发现，如所见的连续切片的配对颞骨2名患者。关于密歇根大学医学中心患者的临床结果和从文献中挑选的病例的详细临床数据已经在前面介绍过了。1-12本报告中的临床耳科发现基于对先前报告的124名患者中的18名患者的研究，占总病例的14.5%(表)。五个病例来自密歇根大学的系列病例。这些结果基本上是慢性中耳和乳突化脓症，通常是输卵管炎伴随鼻咽肉芽肿形成的结果。作为韦格纳致命性中线肉芽肿复合体的特征，这种中耳炎疾病对传统的保守或手术治疗方法无效。合而为一
The purpose of this paper is to describe the otologic features of fatal granulomatosis of the respiratory tract. Particular emphasis is placed upon the pathologic anatomic findings as seen in serial sections of the paired temporal bones of 2 patients with this disease. Clinical Findings Detailed clinical data concerning the University of Michigan Medical Center patients and selected cases from the literature have been presented previously. 1-12 The clinical otologic findings in this report are based upon a study of 18 patients of 124 previously reported, or 14.5% of total cases (Table). Five cases are from the University of Michigan series. The findings are essentially those of chronic middle ear and mastoid suppuration, often the result of salpingitis observed with nasopharyngeal granuloma formation. As is characteristic of Wegener's lethal midline granuloma complex in general, the otitic disease failed to respond to the conventional conservative or surgical therapeutic methods. In one