Dentine hypersensitivity: the measurement in vitro of streaming potentials with fluid flow across dentine and hydroxyapatite.
Dentine hypersensitivity: the measurement in vitro of streaming potentials with fluid flow across dentine and hydroxyapatite.
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牙本质过敏：体外测量流体流过牙本质和羟基磷灰石的流动电位。
DOI：
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发表时间：
1993
影响因子：
3.5
通讯作者：
M. Addy
中科院分区：
文献类型：
--
作者：
H. Griffiths;G. Morgan;K. Williams;M. Addy
在牙本质过敏等情况下，刺激物在牙本质上的传递被认为是通过流体动力学机制发生的。牙本质中的这种流体流动可能会引起牙髓神经中的机械感受器反应。然而，当流体流过多孔结构时也会产生电势。本研究的目的是开发一个可重复的模型系统来测量牙本质和羟基磷灰石的流动潜力并确定压力的影响。使用带有银电极的丙烯酸池，在 1-6 个大气压的压力范围内记录尺寸标准化的牙本质和羟基磷灰石样本的流动电位。发现流动电势与压力成正比，并且取决于电池中使用的盐水的电导率。结果证实了有关牙本质流动电位的有限现有数据，并表明在这些低压下不会发生牙髓神经的兴奋。然而，如果对牙本质施加的刺激产生非常高的压力（可能是这种情况），那么产生的最终电位确实可以引起神经反应。该模型系统值得进一步用于研究这一现象及其影响因素。
Stimulus transmission across dentine, in conditions such as dentine hypersensitivity, is considered to occur via a hydrodynamic mechanism. This fluid flow in dentine may then induce a mechanoreceptor response in pulpal nerves. However, when fluid flows through a porous structure electrical potentials are also generated. The aim of this study was to develop a reproducible model system to measure streaming potential across dentine and hydroxyapatite and determine the influence of pressure. Using an acrylic cell, with silver electrodes, streaming potentials were recorded across dimensionally standardized dentine and hydroxyapatite specimens, over a pressure range of 1-6 atmospheres. Streaming potentials were found to be directly proportional to pressure and dependent on the electrical conductivity of the saline used in the cell. The results confirm the limited existing data on streaming potentials across dentine and indicate that at these low pressures excitation of pulpal nerves would not occur. However, if, as may be the case, stimuli applied to dentine create very high pressures, the resultant potentials generated could indeed evoke a neural response. The model system is worthy of further use to study this phenomenon and the factors which may influence it.
牙本质渗透性：空腔清漆和基质的影响。
DOI：
10.1016/0022-3913(85)90637-7
发表时间：
1985
期刊：
The Journal of prosthetic dentistry
影响因子：
--
作者：
Pashley,DH;O'Meara,JA;Williams,EC;Kepler,EE
通讯作者：
Kepler,EE
影响因子：
4.3
作者：
D. Pashley;J. G. Leibach;J. Horner
通讯作者：
D. Pashley;J. G. Leibach;J. Horner